Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter? / Penny, Jeannette Ø; Overgaard, Søren.

In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials, Vol. 92, No. 1, 01.01.2010, p. 1-4.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Penny, JØ & Overgaard, S 2010, 'Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter?', Journal of Biomedical Materials Research. Part B: Applied Biomaterials, vol. 92, no. 1, pp. 1-4. https://doi.org/10.1002/jbm.b.31479

APA

Penny, J. Ø., & Overgaard, S. (2010). Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter? Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 92(1), 1-4. https://doi.org/10.1002/jbm.b.31479

Vancouver

Penny JØ, Overgaard S. Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter? Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 2010 Jan 1;92(1):1-4. https://doi.org/10.1002/jbm.b.31479

Author

Penny, Jeannette Ø ; Overgaard, Søren. / Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter?. In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 2010 ; Vol. 92, No. 1. pp. 1-4.

Bibtex

@article{4704796195ce4108add928688cd5f35a,
title = "Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter?",
abstract = "PURPOSE: Modern metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory. METHODS: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. RESULTS: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. CONCLUSION: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.",
author = "Penny, {Jeannette {\O}} and S{\o}ren Overgaard",
note = "(c) 2009 Wiley Periodicals, Inc.",
year = "2010",
month = jan,
day = "1",
doi = "10.1002/jbm.b.31479",
language = "English",
volume = "92",
pages = "1--4",
journal = "Journal of Biomedical Materials Research - Part B Applied Biomaterials",
issn = "1552-4973",
publisher = "JohnWiley & Sons, Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Serum chromium levels sampled with steel needle versus plastic IV cannula. Does method matter?

AU - Penny, Jeannette Ø

AU - Overgaard, Søren

N1 - (c) 2009 Wiley Periodicals, Inc.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - PURPOSE: Modern metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory. METHODS: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. RESULTS: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. CONCLUSION: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.

AB - PURPOSE: Modern metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory. METHODS: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. RESULTS: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. CONCLUSION: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.

U2 - 10.1002/jbm.b.31479

DO - 10.1002/jbm.b.31479

M3 - Journal article

C2 - 19802822

VL - 92

SP - 1

EP - 4

JO - Journal of Biomedical Materials Research - Part B Applied Biomaterials

JF - Journal of Biomedical Materials Research - Part B Applied Biomaterials

SN - 1552-4973

IS - 1

ER -

ID: 252049735