Self-Help Plus para Refugiados y solicitantes de asilo: Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales
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Self-Help Plus para Refugiados y solicitantes de asilo : Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales. / Karyotaki, Eirini; Sijbrandij, Marit; Purgato, Marianna; Acarturk, Ceren; Lakin, Daniel; Bailey, Della; Peckham, Emily; Uygun, Ersin; Tedeschi, Federico; Wancata, Johannes; Augustinavicius, Jura; Carswell, Ken; Välimäki, Maritta; van Ommeren, Mark; Koesters, Markus; Popa, Mariana; Leku, Marx Ronald; Anttila, Minna; Churchill, Rachel; White, Ross; Al-Hashimi, Sarah; Lantta, Tella; Au, Teresa; Klein, Thomas; Tol, Wietse A.; Cuijpers, Pim; Barbui, Corrado.
In: European Journal of Psychotraumatology, Vol. 12, No. 1, 1930690, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Self-Help Plus para Refugiados y solicitantes de asilo
T2 - Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales
AU - Karyotaki, Eirini
AU - Sijbrandij, Marit
AU - Purgato, Marianna
AU - Acarturk, Ceren
AU - Lakin, Daniel
AU - Bailey, Della
AU - Peckham, Emily
AU - Uygun, Ersin
AU - Tedeschi, Federico
AU - Wancata, Johannes
AU - Augustinavicius, Jura
AU - Carswell, Ken
AU - Välimäki, Maritta
AU - van Ommeren, Mark
AU - Koesters, Markus
AU - Popa, Mariana
AU - Leku, Marx Ronald
AU - Anttila, Minna
AU - Churchill, Rachel
AU - White, Ross
AU - Al-Hashimi, Sarah
AU - Lantta, Tella
AU - Au, Teresa
AU - Klein, Thomas
AU - Tol, Wietse A.
AU - Cuijpers, Pim
AU - Barbui, Corrado
N1 - Publisher Copyright: © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
AB - Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.
KW - asylum seekers
KW - common mental disorders
KW - depression
KW - individual participant data
KW - Refugees
U2 - 10.1080/20008198.2021.1930690
DO - 10.1080/20008198.2021.1930690
M3 - Journal article
C2 - 34262667
AN - SCOPUS:85109183560
VL - 12
JO - European Journal of Psychotraumatology
JF - European Journal of Psychotraumatology
SN - 2000-8198
IS - 1
M1 - 1930690
ER -
ID: 300398461