Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man

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Standard

Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man. / Henriksen, Jens Henrik Sahl; Kastrup, J; Christensen, N J.

In: Clinical Science, Vol. 68, No. 6, 1985, p. 621-4.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Henriksen, JHS, Kastrup, J & Christensen, NJ 1985, 'Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man', Clinical Science, vol. 68, no. 6, pp. 621-4.

APA

Henriksen, J. H. S., Kastrup, J., & Christensen, N. J. (1985). Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man. Clinical Science, 68(6), 621-4.

Vancouver

Henriksen JHS, Kastrup J, Christensen NJ. Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man. Clinical Science. 1985;68(6):621-4.

Author

Henriksen, Jens Henrik Sahl ; Kastrup, J ; Christensen, N J. / Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man. In: Clinical Science. 1985 ; Vol. 68, No. 6. pp. 621-4.

Bibtex

@article{704bee4038d811dfad7f000ea68e967b,
title = "Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man",
abstract = "1. Plasma noradrenaline and adrenaline concentrations were measured in ten subjects before, during and after intravenous infusion of angiotensin II (ANG II) in order to determine the sympathoadrenal response of ANG II challenge in man. In five subjects ganglionic blockade was additionally performed by intravenous infusion of trimethaphan. 2. During ANG II infusion mean arterial blood pressure increased by 30% (P < 0.001), and plasma noradrenaline decreased by 25% (P < 0.001). Plasma adrenaline decreased less. 3. During ganglionic blockade plasma noradrenaline decreased significantly (P < 0.005) and similarly to the decrease obtained with ANG II infusion. 4. The results indicate that a decrease in sympathoadrenal activity occurs during ANG II-induced acute hypertension in man. This may be elicited by the arterial baroreflex, which seems to dominate any direct sympathoadrenergic facilitating effect of ANG II.",
author = "Henriksen, {Jens Henrik Sahl} and J Kastrup and Christensen, {N J}",
note = "Keywords: Acute Disease; Adult; Aged; Angiotensin II; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine",
year = "1985",
language = "English",
volume = "68",
pages = "621--4",
journal = "Clinical Science",
issn = "0143-5221",
publisher = "Portland Press Ltd.",
number = "6",

}

RIS

TY - JOUR

T1 - Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man

AU - Henriksen, Jens Henrik Sahl

AU - Kastrup, J

AU - Christensen, N J

N1 - Keywords: Acute Disease; Adult; Aged; Angiotensin II; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine

PY - 1985

Y1 - 1985

N2 - 1. Plasma noradrenaline and adrenaline concentrations were measured in ten subjects before, during and after intravenous infusion of angiotensin II (ANG II) in order to determine the sympathoadrenal response of ANG II challenge in man. In five subjects ganglionic blockade was additionally performed by intravenous infusion of trimethaphan. 2. During ANG II infusion mean arterial blood pressure increased by 30% (P < 0.001), and plasma noradrenaline decreased by 25% (P < 0.001). Plasma adrenaline decreased less. 3. During ganglionic blockade plasma noradrenaline decreased significantly (P < 0.005) and similarly to the decrease obtained with ANG II infusion. 4. The results indicate that a decrease in sympathoadrenal activity occurs during ANG II-induced acute hypertension in man. This may be elicited by the arterial baroreflex, which seems to dominate any direct sympathoadrenergic facilitating effect of ANG II.

AB - 1. Plasma noradrenaline and adrenaline concentrations were measured in ten subjects before, during and after intravenous infusion of angiotensin II (ANG II) in order to determine the sympathoadrenal response of ANG II challenge in man. In five subjects ganglionic blockade was additionally performed by intravenous infusion of trimethaphan. 2. During ANG II infusion mean arterial blood pressure increased by 30% (P < 0.001), and plasma noradrenaline decreased by 25% (P < 0.001). Plasma adrenaline decreased less. 3. During ganglionic blockade plasma noradrenaline decreased significantly (P < 0.005) and similarly to the decrease obtained with ANG II infusion. 4. The results indicate that a decrease in sympathoadrenal activity occurs during ANG II-induced acute hypertension in man. This may be elicited by the arterial baroreflex, which seems to dominate any direct sympathoadrenergic facilitating effect of ANG II.

M3 - Journal article

C2 - 2485262

VL - 68

SP - 621

EP - 624

JO - Clinical Science

JF - Clinical Science

SN - 0143-5221

IS - 6

ER -

ID: 18838664