Reduced mortality and CD4 cell loss among carriers of the interleukin-10 -1082G allele in a Zimbabwean cohort of HIV-1-infected adults
Research output: Contribution to journal › Journal article › Research › peer-review
To evaluate the effect on HIV progression of single nucleotide polymorphisms in promoters of the genes for tumour necrosis factor (TNF)-alpha and interleukin (IL)-10 and known to influence cytokine production.
| Original language | English |
|---|---|
| Journal | AIDS |
| Volume | 21 |
| Issue number | 17 |
| Pages (from-to) | 2283-91 |
| Number of pages | 9 |
| ISSN | 0269-9370 |
| DOIs | |
| Publication status | Published - 2007 |
- Adult, Alleles, Analysis of Variance, Biological Markers, CD4 Lymphocyte Count, Case-Control Studies, Developing Countries, Disease Progression, Female, HIV Infections, HIV-1, Haplotypes, Heterozygote, Humans, Interleukin-10, Interleukin-8, Male, Middle Aged, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, Proportional Hazards Models, RNA, Viral, Receptors, Tumor Necrosis Factor, Type II, Survival Rate, Tumor Necrosis Factor-alpha, Virus Replication, Zimbabwe
Research areas
ID: 36143672