RECQL5 helicase: Connections to DNA recombination and RNA polymerase II transcription
Research output: Contribution to journal › Review › Research › peer-review
The RecQ family of helicases are traditionally viewed as recombination factors, important for maintaining genome stability. RECQL5 is unique among these proteins in being associated with RNA polymerase II, the enzyme responsible for transcribing all protein-encoding genes in eukaryotes. Here, we describe the possible implications of recent studies and discuss models for RECQL5 function.
| Original language | English |
|---|---|
| Journal | DNA Repair |
| Volume | 9 |
| Issue number | 3 |
| Pages (from-to) | 345-353 |
| Number of pages | 9 |
| ISSN | 1568-7864 |
| DOIs | |
| Publication status | Published - 2010 |
| Externally published | Yes |
Bibliographical note
Funding Information:
This work was supported by a grant from the Association of International Cancer Research (AICR) and by an in-house grant from Cancer Research UK (to J.Q.S.).
ID: 330899729