Pseudo-observations in survival analysis
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Pseudo-observations in survival analysis. / Andersen, Per Kragh; Perme, Maja Pohar.
In: Statistical Methods in Medical Research, Vol. 19, No. 1, 2010, p. 71-99.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Pseudo-observations in survival analysis
AU - Andersen, Per Kragh
AU - Perme, Maja Pohar
N1 - Keywords: Adult; Bone Marrow Transplantation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Regression Analysis; Risk Assessment; Survival Analysis; Survival Rate; Young Adult
PY - 2010
Y1 - 2010
N2 - We review recent work on the application of pseudo-observations in survival and event history analysis. This includes regression models for parameters like the survival function in a single point, the restricted mean survival time and transition or state occupation probabilities in multi-state models, e.g. the competing risks cumulative incidence function. Graphical and numerical methods for assessing goodness-of-fit for hazard regression models and for the Fine-Gray model in competing risks studies based on pseudo-observations are also reviewed. Sensitivity to covariate-dependent censoring is studied. The methods are illustrated using a data set from bone marrow transplantation.
AB - We review recent work on the application of pseudo-observations in survival and event history analysis. This includes regression models for parameters like the survival function in a single point, the restricted mean survival time and transition or state occupation probabilities in multi-state models, e.g. the competing risks cumulative incidence function. Graphical and numerical methods for assessing goodness-of-fit for hazard regression models and for the Fine-Gray model in competing risks studies based on pseudo-observations are also reviewed. Sensitivity to covariate-dependent censoring is studied. The methods are illustrated using a data set from bone marrow transplantation.
U2 - 10.1177/0962280209105020
DO - 10.1177/0962280209105020
M3 - Journal article
C2 - 19654170
VL - 19
SP - 71
EP - 99
JO - Statistical Methods in Medical Research
JF - Statistical Methods in Medical Research
SN - 0962-2802
IS - 1
ER -
ID: 20738642