Prospective associations between working time arrangements and psychiatric treatment in denmark: Protocol for a cohort study
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Prospective associations between working time arrangements and psychiatric treatment in denmark : Protocol for a cohort study. / Hannerz, Harald; Albertsen, Karen; Nielsen, Martin Lindhardt; Garde, Anne Helene.
In: JMIR Research Protocols, Vol. 9, No. 6, e18236, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Prospective associations between working time arrangements and psychiatric treatment in denmark
T2 - Protocol for a cohort study
AU - Hannerz, Harald
AU - Albertsen, Karen
AU - Nielsen, Martin Lindhardt
AU - Garde, Anne Helene
N1 - Publisher Copyright: © Harald Hannerz, Karen Albertsen, Martin Lindhardt Nielsen, Anne Helene Garde.
PY - 2020
Y1 - 2020
N2 - Background: The burden of mental ill health in working-age populations has prompted research on possible links between work-related factors and mental ill health. Long working hours and night shift work are some of the factors that have been studied in relation to the risk of developing mental ill health. Yet, previous studies have not generated conclusive evidence, and further studies of high quality are needed. Objective: This study aims to investigate the prospective association between working time arrangements and mental health in terms of psychotropic drug usage or psychiatric hospital treatment in the general working population of Denmark. Methods: Data on total weekly working hours in any job and night shift work from the Danish Labor Force Survey 2000-2013 will be linked to data from the Psychiatric Central Research Register (expected 2400 cases during 700,000 person years at risk) and National Prescription Registry (expected 17,400 cases during 600,000 person years at risk). Participants will be followed for up to 5 years. We will use Poisson regression to separately analyze incidence rates of redeemed prescriptions for psychotropic medicine and incidence rates of psychiatric hospital treatment due to mood disorders, anxiety disorders, or stress-related disorders as a function of weekly working hours and night shift work. The analyses will be controlled for sex, age, calendar time of the interview, and socioeconomic status. Results: This is a study protocol. Power calculations indicate that the study has sufficient statistical power to detect relatively small differences in risks and minor interactions (eg, ∼90% power to detect a rate ratio of 1.1 for psychoactive medication use). We expect the analyses to be completed by the end of 2020 and the results to be published in 2021. Conclusions: In this study protocol, all hypotheses and statistical models of the project have been completely defined before we link the exposure data to the outcome data. The results of the project will indicate to what extent and in what direction the national burden of mental ill health in Denmark has been influenced by long working hours and night shift work.
AB - Background: The burden of mental ill health in working-age populations has prompted research on possible links between work-related factors and mental ill health. Long working hours and night shift work are some of the factors that have been studied in relation to the risk of developing mental ill health. Yet, previous studies have not generated conclusive evidence, and further studies of high quality are needed. Objective: This study aims to investigate the prospective association between working time arrangements and mental health in terms of psychotropic drug usage or psychiatric hospital treatment in the general working population of Denmark. Methods: Data on total weekly working hours in any job and night shift work from the Danish Labor Force Survey 2000-2013 will be linked to data from the Psychiatric Central Research Register (expected 2400 cases during 700,000 person years at risk) and National Prescription Registry (expected 17,400 cases during 600,000 person years at risk). Participants will be followed for up to 5 years. We will use Poisson regression to separately analyze incidence rates of redeemed prescriptions for psychotropic medicine and incidence rates of psychiatric hospital treatment due to mood disorders, anxiety disorders, or stress-related disorders as a function of weekly working hours and night shift work. The analyses will be controlled for sex, age, calendar time of the interview, and socioeconomic status. Results: This is a study protocol. Power calculations indicate that the study has sufficient statistical power to detect relatively small differences in risks and minor interactions (eg, ∼90% power to detect a rate ratio of 1.1 for psychoactive medication use). We expect the analyses to be completed by the end of 2020 and the results to be published in 2021. Conclusions: In this study protocol, all hypotheses and statistical models of the project have been completely defined before we link the exposure data to the outcome data. The results of the project will indicate to what extent and in what direction the national burden of mental ill health in Denmark has been influenced by long working hours and night shift work.
KW - Anxiety
KW - Long working hours
KW - Mood disorders
KW - Night shift work
KW - Occupational health
KW - Prescription drugs
KW - Psychiatric hospital treatment
KW - Psychotropic medicine
KW - Stress-related disorders
U2 - 10.2196/18236
DO - 10.2196/18236
M3 - Journal article
AN - SCOPUS:85091969435
VL - 9
JO - J M I R Research Protocols
JF - J M I R Research Protocols
SN - 1929-0748
IS - 6
M1 - e18236
ER -
ID: 387296347