Primary fibromyalgia: clinical parameters in relation to serum procollagen type III aminoterminal peptide
Research output: Contribution to journal › Journal article › Research › peer-review
Serum concentrations of procollagen type III aminoterminal peptide have previously been reported to be low in some patients with primary fibromyalgia and the aim of this study was to determine if such patients differ clinically from primary fibromyalgia patients with normal levels of procollagen type III aminoterminal peptide. Subjective symptoms, tender points and dynamic muscle strength in 45 women with primary fibromyalgia were related to serum concentrations of procollagen type III aminoterminal peptide. Patients with low serum concentrations of procollagen type III aminoterminal peptide had more symptoms, a higher frequency of tender points and lesser quality of sleep compared to patients with normal serum concentrations of procollagen type III aminoterminal peptide (P less than 0.05). They also had a lower dynamic muscle strength (P less than 0.0005). We conclude that the serum concentrations of procollagen type III aminoterminal peptide of primary fibromyalgia patients are connected to the disease impact.
Original language | English |
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Journal | British Journal of Rheumatology |
Volume | 29 |
Issue number | 3 |
Pages (from-to) | 174-7 |
Number of pages | 4 |
ISSN | 0263-7103 |
Publication status | Published - Jun 1990 |
- Adult, Aged, Female, Fibromyalgia, Humans, Middle Aged, Muscles, Pain, Peptide Fragments, Procollagen, Sleep Wake Disorders, Journal Article, Research Support, Non-U.S. Gov't
Research areas
ID: 168533529