Permeability and ultrastructure of human bladder epithelium
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Permeability and ultrastructure of human bladder epithelium. / Eldrup, J; Thorup, Jørgen Mogens; Nielsen, S L; Hald, T; Hainau, B.
In: British Journal of Urology, Vol. 55, No. 5, 10.1983, p. 488-92.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Permeability and ultrastructure of human bladder epithelium
AU - Eldrup, J
AU - Thorup, Jørgen Mogens
AU - Nielsen, S L
AU - Hald, T
AU - Hainau, B
PY - 1983/10
Y1 - 1983/10
N2 - Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.
AB - Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.
KW - Adult
KW - Albumins
KW - Cell Membrane Permeability
KW - Epithelium
KW - Female
KW - Humans
KW - Intercellular Junctions
KW - Male
KW - Microscopy, Electron
KW - Middle Aged
KW - Sodium
KW - Urea
KW - Urinary Bladder
KW - Urologic Diseases
M3 - Journal article
C2 - 6626894
VL - 55
SP - 488
EP - 492
JO - British Journal of Urology
JF - British Journal of Urology
SN - 0007-1331
IS - 5
ER -
ID: 47629792