Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis

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Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis. / Graff, J; Fugleberg, S; Joffe, P; Brahm, J; Fogh-Andersen, N.

In: Clinical physiology (Oxford, England), Vol. 15, No. 3, 05.1995, p. 185-97.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Graff, J, Fugleberg, S, Joffe, P, Brahm, J & Fogh-Andersen, N 1995, 'Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis', Clinical physiology (Oxford, England), vol. 15, no. 3, pp. 185-97.

APA

Graff, J., Fugleberg, S., Joffe, P., Brahm, J., & Fogh-Andersen, N. (1995). Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis. Clinical physiology (Oxford, England), 15(3), 185-97.

Vancouver

Graff J, Fugleberg S, Joffe P, Brahm J, Fogh-Andersen N. Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis. Clinical physiology (Oxford, England). 1995 May;15(3):185-97.

Author

Graff, J ; Fugleberg, S ; Joffe, P ; Brahm, J ; Fogh-Andersen, N. / Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis. In: Clinical physiology (Oxford, England). 1995 ; Vol. 15, No. 3. pp. 185-97.

Bibtex

@article{118d8d1f67144367bc019d1fe9578e15,
title = "Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis",
abstract = "The mechanisms of transperitoneal potassium transport during peritoneal dialysis were evaluated by validation of different mathematical models. The models were designed to elucidate the presence or absence of diffusive, non-lymphatic convective and lymphatic convective solute transport. Experimental results were obtained from 26 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that models including both diffusive and non-lymphatic convective solute transport were superior to the other models. Lymphatic convective solute transport was not identifiable. Furthermore, it was demonstrated experimentally that the equilibrium distribution of potassium between plasma water and dialysate did not differ from a Donnan equilibrium, although the precondition of the Donnan equilibrium was not fulfilled, i.e. the volumes on each side of the membrane were not constant and dialysate was not an ultrafiltrate of plasma.",
keywords = "Adult, Aged, Diffusion, Female, Humans, Male, Middle Aged, Models, Biological, Peritoneal Dialysis, Potassium, Ultrafiltration",
author = "J Graff and S Fugleberg and P Joffe and J Brahm and N Fogh-Andersen",
year = "1995",
month = may,
language = "English",
volume = "15",
pages = "185--97",
journal = "Clinical Physiology",
issn = "0144-5979",
publisher = "Blackwell Science Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Parameter estimation in six numerical models of transperitoneal transport of potassium in patients undergoing peritoneal dialysis

AU - Graff, J

AU - Fugleberg, S

AU - Joffe, P

AU - Brahm, J

AU - Fogh-Andersen, N

PY - 1995/5

Y1 - 1995/5

N2 - The mechanisms of transperitoneal potassium transport during peritoneal dialysis were evaluated by validation of different mathematical models. The models were designed to elucidate the presence or absence of diffusive, non-lymphatic convective and lymphatic convective solute transport. Experimental results were obtained from 26 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that models including both diffusive and non-lymphatic convective solute transport were superior to the other models. Lymphatic convective solute transport was not identifiable. Furthermore, it was demonstrated experimentally that the equilibrium distribution of potassium between plasma water and dialysate did not differ from a Donnan equilibrium, although the precondition of the Donnan equilibrium was not fulfilled, i.e. the volumes on each side of the membrane were not constant and dialysate was not an ultrafiltrate of plasma.

AB - The mechanisms of transperitoneal potassium transport during peritoneal dialysis were evaluated by validation of different mathematical models. The models were designed to elucidate the presence or absence of diffusive, non-lymphatic convective and lymphatic convective solute transport. Experimental results were obtained from 26 non-diabetic patients undergoing peritoneal dialysis. The validation procedure demonstrated that models including both diffusive and non-lymphatic convective solute transport were superior to the other models. Lymphatic convective solute transport was not identifiable. Furthermore, it was demonstrated experimentally that the equilibrium distribution of potassium between plasma water and dialysate did not differ from a Donnan equilibrium, although the precondition of the Donnan equilibrium was not fulfilled, i.e. the volumes on each side of the membrane were not constant and dialysate was not an ultrafiltrate of plasma.

KW - Adult

KW - Aged

KW - Diffusion

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Models, Biological

KW - Peritoneal Dialysis

KW - Potassium

KW - Ultrafiltration

M3 - Journal article

C2 - 7621641

VL - 15

SP - 185

EP - 197

JO - Clinical Physiology

JF - Clinical Physiology

SN - 0144-5979

IS - 3

ER -

ID: 94518965