Out-of-hospital cardiac arrest related to exercise in the general population: Incidence, survival and bystander response
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Out-of-hospital cardiac arrest related to exercise in the general population : Incidence, survival and bystander response. / Wolthers, Signe Amalie; Jensen, Theo Walther; Blomberg, Stig Nikolaj; Holgersen, Mathias Gelderman; Lippert, Freddy; Mikkelsen, Søren; Hendriksen, Ole Mazur; Torp-Pedersen, Christian; Christensen, Helle Collatz.
In: Resuscitation, Vol. 172, 2022, p. 84-91.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Out-of-hospital cardiac arrest related to exercise in the general population
T2 - Incidence, survival and bystander response
AU - Wolthers, Signe Amalie
AU - Jensen, Theo Walther
AU - Blomberg, Stig Nikolaj
AU - Holgersen, Mathias Gelderman
AU - Lippert, Freddy
AU - Mikkelsen, Søren
AU - Hendriksen, Ole Mazur
AU - Torp-Pedersen, Christian
AU - Christensen, Helle Collatz
N1 - Publisher Copyright: © 2022 The Authors
PY - 2022
Y1 - 2022
N2 - Background: Regular exercise is known to prevent cardiovascular disorders, but it may also trigger acute cardiac events. This study examined the incidence, prognosis, and outcomes of out-of-hospital cardiac arrest (OHCA) related to exercise in the general population of Denmark. Methods: This retrospective cohort study examined all the OHCAs in the Danish Cardiac Arrest Registry from 2016 to 2019. OHCA related to exercise was identified in a nationwide electronic database and coupled to the patient register. Descriptive statistics were used in combination with a multivariate logistic regression model to assess predefined factors. Results: A total of 20,470 OHCAs were identified, of which 459 (2.2%) were related to exercise. Most were male (75.3%), with a median age of 61 years. Further, 95% of exercise-related OHCA received bystander cardiopulmonary resuscitation, compared to 77.4% in non-exercise-related OHCA (p < 0.001), and 38.3% received defibrillation by bystanders versus 7.5% in the non-exercise group (p < 0.001). Exercise-related OHCAs had a 30-day survival rate of 57.7% compared to 12.6% in the non-exercise group, yielding an adjusted odds ratio of 5.56. The 30-day survival rate of exercise-related subjects aged 15–35 years was 80.0%, compared to 25.0% in the non-exercise group. When comparing sports categories, team sports were associated with the greatest chance of survival (odds ratio of 18.5 versus a non-exercise odds ratio of 0.09). Conclusion: Exercise-related OHCA has a low incidence and is related to a significantly better prognosis when compared to non-exercise OHCA. Furthermore, many patients experiencing exercise-related OHCA received defibrillation and cardiopulmonary resuscitation by bystanders. These findings could help plan and execute campaigns and education.
AB - Background: Regular exercise is known to prevent cardiovascular disorders, but it may also trigger acute cardiac events. This study examined the incidence, prognosis, and outcomes of out-of-hospital cardiac arrest (OHCA) related to exercise in the general population of Denmark. Methods: This retrospective cohort study examined all the OHCAs in the Danish Cardiac Arrest Registry from 2016 to 2019. OHCA related to exercise was identified in a nationwide electronic database and coupled to the patient register. Descriptive statistics were used in combination with a multivariate logistic regression model to assess predefined factors. Results: A total of 20,470 OHCAs were identified, of which 459 (2.2%) were related to exercise. Most were male (75.3%), with a median age of 61 years. Further, 95% of exercise-related OHCA received bystander cardiopulmonary resuscitation, compared to 77.4% in non-exercise-related OHCA (p < 0.001), and 38.3% received defibrillation by bystanders versus 7.5% in the non-exercise group (p < 0.001). Exercise-related OHCAs had a 30-day survival rate of 57.7% compared to 12.6% in the non-exercise group, yielding an adjusted odds ratio of 5.56. The 30-day survival rate of exercise-related subjects aged 15–35 years was 80.0%, compared to 25.0% in the non-exercise group. When comparing sports categories, team sports were associated with the greatest chance of survival (odds ratio of 18.5 versus a non-exercise odds ratio of 0.09). Conclusion: Exercise-related OHCA has a low incidence and is related to a significantly better prognosis when compared to non-exercise OHCA. Furthermore, many patients experiencing exercise-related OHCA received defibrillation and cardiopulmonary resuscitation by bystanders. These findings could help plan and execute campaigns and education.
KW - Bystander CPR
KW - Defibrillation
KW - Emergency Medical Service
KW - Exercise
KW - Out-of-hospital cardiac arrest
KW - Outcome after OHCA
KW - Resuscitation
U2 - 10.1016/j.resuscitation.2022.01.021
DO - 10.1016/j.resuscitation.2022.01.021
M3 - Journal article
C2 - 35090970
AN - SCOPUS:85124076766
VL - 172
SP - 84
EP - 91
JO - Resuscitation
JF - Resuscitation
SN - 0300-9572
ER -
ID: 299825668