Opportunistic infections and malignancies in 231 Danish AIDS patients.
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Opportunistic infections and malignancies in 231 Danish AIDS patients. / Pedersen, C; Gerstoft, J; Tauris, P; Lundgren, Jens Dilling; Gøtzsche, P C; Buhl, M; Salim, Yussuf Saleh; Schmidt, K.
In: AIDS, Vol. 4, No. 3, 1990, p. 233-238.Research output: Contribution to journal › Journal article › Research
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TY - JOUR
T1 - Opportunistic infections and malignancies in 231 Danish AIDS patients.
AU - Pedersen, C
AU - Gerstoft, J
AU - Tauris, P
AU - Lundgren, Jens Dilling
AU - Gøtzsche, P C
AU - Buhl, M
AU - Salim, Yussuf Saleh
AU - Schmidt, K
PY - 1990
Y1 - 1990
N2 - We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.
AB - We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.
M3 - Journal article
VL - 4
SP - 233
EP - 238
JO - AIDS
JF - AIDS
SN - 1350-2840
IS - 3
ER -
ID: 40213199