No influence of GB virus C on disease progression in a Danish cohort of HIV-infected men
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No influence of GB virus C on disease progression in a Danish cohort of HIV-infected men. / Ryt-Hansen, Rosa; Katzenstein, Terese L; Gerstoft, Jan; Eugen-Olsen, Jesper.
In: AIDS Research and Human Retroviruses, Vol. 22, No. 6, 2006, p. 496-498.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - No influence of GB virus C on disease progression in a Danish cohort of HIV-infected men
AU - Ryt-Hansen, Rosa
AU - Katzenstein, Terese L
AU - Gerstoft, Jan
AU - Eugen-Olsen, Jesper
N1 - Paper id:: PMID: 16796523
PY - 2006
Y1 - 2006
N2 - Presumed apathogenic viruses have been suggested to play a role in HIV infection. In some cohorts of HIVpositive patients, GB virus C (GBVC) has been associated with prolonged survival and time to AIDS. We set out to address whether GBVC infection had any influence on survival in a cohort of 112 homosexual white HIV-1 positive Danish men. Patients were enrolled between 1984 and 1987 and followed for a mean of 6.7 years. Follow-up was censored in May 1996 when the first patient in the cohort received HAART. Plasma samples were screened at baseline using polymerase chain reaction methods for GBVC. Of the 112 patients, 27 (24%) were positive for GBVC. No difference in time to AIDS or death was observed between the GBVCnegative and -positive patients. Furthermore, no difference in CD4+ T cell decline was observed in the first year following blood sampling between the GBVC-positive and -negative groups
AB - Presumed apathogenic viruses have been suggested to play a role in HIV infection. In some cohorts of HIVpositive patients, GB virus C (GBVC) has been associated with prolonged survival and time to AIDS. We set out to address whether GBVC infection had any influence on survival in a cohort of 112 homosexual white HIV-1 positive Danish men. Patients were enrolled between 1984 and 1987 and followed for a mean of 6.7 years. Follow-up was censored in May 1996 when the first patient in the cohort received HAART. Plasma samples were screened at baseline using polymerase chain reaction methods for GBVC. Of the 112 patients, 27 (24%) were positive for GBVC. No difference in time to AIDS or death was observed between the GBVCnegative and -positive patients. Furthermore, no difference in CD4+ T cell decline was observed in the first year following blood sampling between the GBVC-positive and -negative groups
U2 - http://dx.doi.org/10.1089/aid.2006.22.496
DO - http://dx.doi.org/10.1089/aid.2006.22.496
M3 - Journal article
VL - 22
SP - 496
EP - 498
JO - AIDS Research and Human Retroviruses
JF - AIDS Research and Human Retroviruses
SN - 0889-2229
IS - 6
ER -
ID: 34171870