TY - JOUR

T1 - Myokines in Myogenesis and Health

AU - Henriksen, Tora

AU - Green, Charlotte

AU - Pedersen, Bente Klarlund

PY - 2012

Y1 - 2012

N2 - Although some myokines exert their actions on other organs in a hormone-like fashion, many of them operate locally on skeletal muscle themselves. Myokines may thereby provide a feedback loop for the muscle to regulate its own growth and regeneration allowing for adaptation to exercise training. The myokine concept provides a conceptual basis and a whole new paradigm for understanding how muscles communicate with other organs within the muscle itself. New biotechnological patents are published based on the identification of new myokines, and these myokines and their receptors will potentially serve as pharmacological targets for treating muscle diseases, metabolic disorders and other diseases associated with muscle disuse.

AB - Although some myokines exert their actions on other organs in a hormone-like fashion, many of them operate locally on skeletal muscle themselves. Myokines may thereby provide a feedback loop for the muscle to regulate its own growth and regeneration allowing for adaptation to exercise training. The myokine concept provides a conceptual basis and a whole new paradigm for understanding how muscles communicate with other organs within the muscle itself. New biotechnological patents are published based on the identification of new myokines, and these myokines and their receptors will potentially serve as pharmacological targets for treating muscle diseases, metabolic disorders and other diseases associated with muscle disuse.

M3 - Journal article

VL - 6

SP - 167

EP - 171

JO - Recent Patents on Biotechnology

JF - Recent Patents on Biotechnology

SN - 1872-2083

IS - 3

ER -