Milk protein complexation enhances post prandial vitamin D3absorption in rats

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Milk protein complexation enhances post prandial vitamin D3absorption in rats. / Lindahl, Ida Emilie I.; Danielsen, Marianne; Dalsgaard, Trine K.; Rejnmark, Lars; Bollen, Peter; Bertram, Hanne Christine.

In: Food and Function, Vol. 11, No. 6, 06.2020, p. 4953-4959.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lindahl, IEI, Danielsen, M, Dalsgaard, TK, Rejnmark, L, Bollen, P & Bertram, HC 2020, 'Milk protein complexation enhances post prandial vitamin D3absorption in rats', Food and Function, vol. 11, no. 6, pp. 4953-4959. https://doi.org/10.1039/d0fo01062f

APA

Lindahl, I. E. I., Danielsen, M., Dalsgaard, T. K., Rejnmark, L., Bollen, P., & Bertram, H. C. (2020). Milk protein complexation enhances post prandial vitamin D3absorption in rats. Food and Function, 11(6), 4953-4959. https://doi.org/10.1039/d0fo01062f

Vancouver

Lindahl IEI, Danielsen M, Dalsgaard TK, Rejnmark L, Bollen P, Bertram HC. Milk protein complexation enhances post prandial vitamin D3absorption in rats. Food and Function. 2020 Jun;11(6):4953-4959. https://doi.org/10.1039/d0fo01062f

Author

Lindahl, Ida Emilie I. ; Danielsen, Marianne ; Dalsgaard, Trine K. ; Rejnmark, Lars ; Bollen, Peter ; Bertram, Hanne Christine. / Milk protein complexation enhances post prandial vitamin D3absorption in rats. In: Food and Function. 2020 ; Vol. 11, No. 6. pp. 4953-4959.

Bibtex

@article{f8ec0697dbbf449a9865e4f0ef05e91a,
title = "Milk protein complexation enhances post prandial vitamin D3absorption in rats",
abstract = "This study investigated the effect of complexation with whey and casein protein, respectively, on post prandial absorption of vitamin D3. For this purpose, Sprague-Dawley rats (n = 78) were administered 840 IU vitamin D3 dissolved in ethanol and either (i) complexed with whey protein isolate (protein?:?vitamin ration 2?:?1), (ii) complexed with caseinate (protein?:?vitamin ration 2?:?1), or (iii) provided in a water solution. Serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were measured before and 2, 3, 4, 5, 6, 7, 8, and 10 hours after administration of vitamin D3. Significant effects of complexation on serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were demonstrated. Complexation with whey protein isolate resulted in the fastest and highest absorption of vitamin D3 while an effect of complexation with caseinate was evident but more modest and non-significant. In conclusion, the study demonstrates that complexation with milk proteins is an efficient strategy to enhance bioaccessibility of vitamin D3. This journal is ",
author = "Lindahl, {Ida Emilie I.} and Marianne Danielsen and Dalsgaard, {Trine K.} and Lars Rejnmark and Peter Bollen and Bertram, {Hanne Christine}",
note = "Funding Information: The present study was part of the DFORT project (J-nr. 4105-00008B) supported by Innovation Fund Denmark. Arla Food Ingredients and DSM are thanked for providing milk protein sources and vitamin D, respectively, for the study. We thank Nina Eggers, Caroline Nebel, Anne Mette Durand and Camilla Rasmussen for skillful technical assistance. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2020",
month = jun,
doi = "10.1039/d0fo01062f",
language = "English",
volume = "11",
pages = "4953--4959",
journal = "Food & Function",
issn = "2042-6496",
publisher = "Royal Society of Chemistry",
number = "6",

}

RIS

TY - JOUR

T1 - Milk protein complexation enhances post prandial vitamin D3absorption in rats

AU - Lindahl, Ida Emilie I.

AU - Danielsen, Marianne

AU - Dalsgaard, Trine K.

AU - Rejnmark, Lars

AU - Bollen, Peter

AU - Bertram, Hanne Christine

N1 - Funding Information: The present study was part of the DFORT project (J-nr. 4105-00008B) supported by Innovation Fund Denmark. Arla Food Ingredients and DSM are thanked for providing milk protein sources and vitamin D, respectively, for the study. We thank Nina Eggers, Caroline Nebel, Anne Mette Durand and Camilla Rasmussen for skillful technical assistance. Publisher Copyright: © The Royal Society of Chemistry.

PY - 2020/6

Y1 - 2020/6

N2 - This study investigated the effect of complexation with whey and casein protein, respectively, on post prandial absorption of vitamin D3. For this purpose, Sprague-Dawley rats (n = 78) were administered 840 IU vitamin D3 dissolved in ethanol and either (i) complexed with whey protein isolate (protein?:?vitamin ration 2?:?1), (ii) complexed with caseinate (protein?:?vitamin ration 2?:?1), or (iii) provided in a water solution. Serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were measured before and 2, 3, 4, 5, 6, 7, 8, and 10 hours after administration of vitamin D3. Significant effects of complexation on serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were demonstrated. Complexation with whey protein isolate resulted in the fastest and highest absorption of vitamin D3 while an effect of complexation with caseinate was evident but more modest and non-significant. In conclusion, the study demonstrates that complexation with milk proteins is an efficient strategy to enhance bioaccessibility of vitamin D3. This journal is

AB - This study investigated the effect of complexation with whey and casein protein, respectively, on post prandial absorption of vitamin D3. For this purpose, Sprague-Dawley rats (n = 78) were administered 840 IU vitamin D3 dissolved in ethanol and either (i) complexed with whey protein isolate (protein?:?vitamin ration 2?:?1), (ii) complexed with caseinate (protein?:?vitamin ration 2?:?1), or (iii) provided in a water solution. Serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were measured before and 2, 3, 4, 5, 6, 7, 8, and 10 hours after administration of vitamin D3. Significant effects of complexation on serum concentrations of vitamin D3, 25-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 were demonstrated. Complexation with whey protein isolate resulted in the fastest and highest absorption of vitamin D3 while an effect of complexation with caseinate was evident but more modest and non-significant. In conclusion, the study demonstrates that complexation with milk proteins is an efficient strategy to enhance bioaccessibility of vitamin D3. This journal is

U2 - 10.1039/d0fo01062f

DO - 10.1039/d0fo01062f

M3 - Journal article

C2 - 32500128

AN - SCOPUS:85087111176

VL - 11

SP - 4953

EP - 4959

JO - Food & Function

JF - Food & Function

SN - 2042-6496

IS - 6

ER -

ID: 323446496