Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. / Christiansen, Ole B; Kolte, Astrid M; Dahl, Mette; Larsen, Elisabeth C; Steffensen, Rudi; Nielsen, Henriette S; Hviid, Thomas V.

In: Human Immunology, Vol. 73, No. 7, 07.2012, p. 699-705.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Christiansen, OB, Kolte, AM, Dahl, M, Larsen, EC, Steffensen, R, Nielsen, HS & Hviid, TV 2012, 'Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients', Human Immunology, vol. 73, no. 7, pp. 699-705. https://doi.org/10.1016/j.humimm.2012.04.014

APA

Christiansen, O. B., Kolte, A. M., Dahl, M., Larsen, E. C., Steffensen, R., Nielsen, H. S., & Hviid, T. V. (2012). Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. Human Immunology, 73(7), 699-705. https://doi.org/10.1016/j.humimm.2012.04.014

Vancouver

Christiansen OB, Kolte AM, Dahl M, Larsen EC, Steffensen R, Nielsen HS et al. Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. Human Immunology. 2012 Jul;73(7):699-705. https://doi.org/10.1016/j.humimm.2012.04.014

Author

Christiansen, Ole B ; Kolte, Astrid M ; Dahl, Mette ; Larsen, Elisabeth C ; Steffensen, Rudi ; Nielsen, Henriette S ; Hviid, Thomas V. / Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients. In: Human Immunology. 2012 ; Vol. 73, No. 7. pp. 699-705.

Bibtex

@article{224a29de9e6d49f38be05ea2e9fa3538,
title = "Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients",
abstract = "Homozygous carriage of a 14 base pair (bp) insertion in exon 8 of the HLA-G gene may be associated with low levels of soluble HLA-G and recurrent miscarriage (RM). We investigated the G14bp insertion(ins)/deletion(del) polymorphism in 339 women with unexplained RM and 125 control women. In all patients and patients with secondary RM after a firstborn boy, 19.2% and 23.9%, respectively, were G14bp ins/ins compared with 11.2% of controls (p",
keywords = "Abortion, Habitual, Alleles, DNA Mutational Analysis, Female, Genetic Predisposition to Disease, H-Y Antigen, HLA-G Antigens, Histocompatibility Antigens Class II, Homozygote, Humans, Immunity, Infant, Low Birth Weight, Infant, Newborn, Male, Mutagenesis, Insertional, Polymorphism, Genetic, Protein Binding",
author = "Christiansen, {Ole B} and Kolte, {Astrid M} and Mette Dahl and Larsen, {Elisabeth C} and Rudi Steffensen and Nielsen, {Henriette S} and Hviid, {Thomas V}",
note = "Copyright {\textcopyright} 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.",
year = "2012",
month = jul,
doi = "10.1016/j.humimm.2012.04.014",
language = "English",
volume = "73",
pages = "699--705",
journal = "Human Immunology",
issn = "0198-8859",
publisher = "Elsevier",
number = "7",

}

RIS

TY - JOUR

T1 - Maternal homozygocity for a 14 base pair insertion in exon 8 of the HLA-G gene and carriage of HLA class II alleles restricting HY immunity predispose to unexplained secondary recurrent miscarriage and low birth weight in children born to these patients

AU - Christiansen, Ole B

AU - Kolte, Astrid M

AU - Dahl, Mette

AU - Larsen, Elisabeth C

AU - Steffensen, Rudi

AU - Nielsen, Henriette S

AU - Hviid, Thomas V

N1 - Copyright © 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

PY - 2012/7

Y1 - 2012/7

N2 - Homozygous carriage of a 14 base pair (bp) insertion in exon 8 of the HLA-G gene may be associated with low levels of soluble HLA-G and recurrent miscarriage (RM). We investigated the G14bp insertion(ins)/deletion(del) polymorphism in 339 women with unexplained RM and 125 control women. In all patients and patients with secondary RM after a firstborn boy, 19.2% and 23.9%, respectively, were G14bp ins/ins compared with 11.2% of controls (p

AB - Homozygous carriage of a 14 base pair (bp) insertion in exon 8 of the HLA-G gene may be associated with low levels of soluble HLA-G and recurrent miscarriage (RM). We investigated the G14bp insertion(ins)/deletion(del) polymorphism in 339 women with unexplained RM and 125 control women. In all patients and patients with secondary RM after a firstborn boy, 19.2% and 23.9%, respectively, were G14bp ins/ins compared with 11.2% of controls (p

KW - Abortion, Habitual

KW - Alleles

KW - DNA Mutational Analysis

KW - Female

KW - Genetic Predisposition to Disease

KW - H-Y Antigen

KW - HLA-G Antigens

KW - Histocompatibility Antigens Class II

KW - Homozygote

KW - Humans

KW - Immunity

KW - Infant, Low Birth Weight

KW - Infant, Newborn

KW - Male

KW - Mutagenesis, Insertional

KW - Polymorphism, Genetic

KW - Protein Binding

U2 - 10.1016/j.humimm.2012.04.014

DO - 10.1016/j.humimm.2012.04.014

M3 - Journal article

C2 - 22537754

VL - 73

SP - 699

EP - 705

JO - Human Immunology

JF - Human Immunology

SN - 0198-8859

IS - 7

ER -

ID: 47923510