Long-term trends in the incidence of type 1 diabetes in Denmark: the seasonal variation changes over time
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There is a worldwide increase of type 1 diabetes mellitus (T1DM). In 1996, the Danish population-based registry was initiated including all newly diagnosed children aged 0-15 yr. This is the report of incidence and seasonal variation for the first 10 yr of the registry. The data was analyzed using Poisson's regression analysis. A total of 2166 children with diabetes were diagnosed before the age of 15 yr between 1996 and 2005. In this period, the annual increase in childhood T1DM was 3.43% (95% confidence interval: 1.91-4.97), which was unaffected by age and gender. Seasonal variation in incidence rates varied by year but not by age and gender. In conclusion, there is a steep increase in incidence of childhood T1DM in Denmark; the increase is comparable with the increase seen in other European countries. There is a significant seasonal variation that changes on a year-to-year basis. The observed variations in cadence rates may be associated with viral epidemics, sunshine exposure, or vitamin D levels and suggest further exploration of these relations.
Original language | English |
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Journal | Pediatric Diabetes |
Volume | 10 |
Issue number | 4 |
Pages (from-to) | 248-54 |
Number of pages | 6 |
ISSN | 1399-543X |
DOIs | |
Publication status | Published - 2009 |
Bibliographical note
Keywords: Adolescent; Child; Child, Preschool; Denmark; Diabetes Mellitus, Type 1; Female; Forecasting; Humans; Incidence; Infant; Infant, Newborn; Male; Registries; Seasons; Time Factors
ID: 21336936