Interstitial Lung Abnormalities in People With HIV Infection and Uninfected Controls
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Interstitial Lung Abnormalities in People With HIV Infection and Uninfected Controls. / Ronit, Andreas; Benfield, Thomas; Lundgren, Jens; Vestbo, Jørgen; Afzal, Shoaib; Nordestgaard, Børge G; Kühl, Jørgen Tobias; Kofoed, Klaus F; Nielsen, Susanne Dam; Kristensen, Thomas.
In: The Journal of Infectious Diseases, Vol. 221, No. 12, 2020, p. 1973-1977.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Interstitial Lung Abnormalities in People With HIV Infection and Uninfected Controls
AU - Ronit, Andreas
AU - Benfield, Thomas
AU - Lundgren, Jens
AU - Vestbo, Jørgen
AU - Afzal, Shoaib
AU - Nordestgaard, Børge G
AU - Kühl, Jørgen Tobias
AU - Kofoed, Klaus F
AU - Nielsen, Susanne Dam
AU - Kristensen, Thomas
N1 - © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
PY - 2020
Y1 - 2020
N2 - BACKGROUND: Chest computed tomography (CT) findings in well-treated people with HIV infection (PWH) remain poorly characterized.METHODS: Cross-sectional analysis examining interstitial chest CT findings in PWH (n = 754) and uninfected controls (n = 470).RESULTS: HIV infection was independently associated with 1.82 (95% CI, 1.18-2.88) and 5.15 (95% CI, 1.72-22.2) higher adjusted odds of any interstitial lung abnormality and findings suspicious for interstitial lung disease, respectively.CONCLUSIONS: HIV infection was independently associated with interstitial lung abnormalities and findings suspicious for interstitial lung disease. Whether these abnormalities develop into more recognizable disease states over time is unknown but warrants further investigation.
AB - BACKGROUND: Chest computed tomography (CT) findings in well-treated people with HIV infection (PWH) remain poorly characterized.METHODS: Cross-sectional analysis examining interstitial chest CT findings in PWH (n = 754) and uninfected controls (n = 470).RESULTS: HIV infection was independently associated with 1.82 (95% CI, 1.18-2.88) and 5.15 (95% CI, 1.72-22.2) higher adjusted odds of any interstitial lung abnormality and findings suspicious for interstitial lung disease, respectively.CONCLUSIONS: HIV infection was independently associated with interstitial lung abnormalities and findings suspicious for interstitial lung disease. Whether these abnormalities develop into more recognizable disease states over time is unknown but warrants further investigation.
KW - Aged
KW - Anti-HIV Agents/therapeutic use
KW - Cross-Sectional Studies
KW - Female
KW - HIV Infections/complications
KW - Humans
KW - Lung/diagnostic imaging
KW - Lung Diseases, Interstitial/diagnosis
KW - Male
KW - Middle Aged
KW - Prevalence
KW - Risk Assessment
KW - Tomography, X-Ray Computed
U2 - 10.1093/infdis/jiaa047
DO - 10.1093/infdis/jiaa047
M3 - Journal article
C2 - 32002544
VL - 221
SP - 1973
EP - 1977
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
SN - 0022-1899
IS - 12
ER -
ID: 259515508