Interpretation of composite endpoints in urology: an analysis of citation quality
Research output: Contribution to journal › Journal article › Research › peer-review
Objective: To investigate how urological studies using composite endpoints as the primary outcome were cited. Materials and methods: In this quality analysis of citations, three randomized clinical trials each investigating oncological and non-oncological urology were selected for citation analysis based on pre-defined criteria. In total, 531 papers citing the selected studies were reviewed; citations were evaluated based on whether they correctly referred to the composite endpoint and if singleton endpoints were defined and/or discussed. Results: Among the citations, 223/531 (42%) referred to the composite endpoint, of which 217/223 (97.3%) correctly cited the composite endpoint. However, only 91/217 (41.9%) defined and/or discussed the singleton endpoints of the composite endpoint. The lack of a validated instrument for citation analysis was a limitation of this study. Meanwhile, the main strength is the large number of individually analyzed citations. Conclusions: The composite endpoints of urological randomized clinical trials are generally cited without referring to the composite endpoint; when cited, the composite endpoints are described correctly. However, in most cases, without defining or discussing the singleton endpoints.
Original language | English |
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Journal | Scandinavian Journal of Urology |
Volume | 56 |
Issue number | 3 |
Pages (from-to) | 206-212 |
Number of pages | 7 |
ISSN | 2168-1805 |
DOIs | |
Publication status | Published - 2022 |
Bibliographical note
Publisher Copyright:
© 2022 Acta Chirurgica Scandinavica Society.
- citations, composite endpoints, endpoints, Randomized controlled trials, urology
Research areas
ID: 313651118