Internally organized mechanisms of the head direction sense

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Internally organized mechanisms of the head direction sense. / Petersen, Peter Christian.

In: Nature Neuroscience, Vol. 18, 2015, p. 569-575.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Petersen, PC 2015, 'Internally organized mechanisms of the head direction sense', Nature Neuroscience, vol. 18, pp. 569-575. https://doi.org/10.1038/nn.3968

APA

Petersen, P. C. (2015). Internally organized mechanisms of the head direction sense. Nature Neuroscience, 18, 569-575. https://doi.org/10.1038/nn.3968

Vancouver

Petersen PC. Internally organized mechanisms of the head direction sense. Nature Neuroscience. 2015;18:569-575. https://doi.org/10.1038/nn.3968

Author

Petersen, Peter Christian. / Internally organized mechanisms of the head direction sense. In: Nature Neuroscience. 2015 ; Vol. 18. pp. 569-575.

Bibtex

@article{5a7c259b547a4f11a87ccc4e958730e2,
title = "Internally organized mechanisms of the head direction sense",
abstract = "The head-direction (HD) system functions as a compass, with member neurons robustly increasing their firing rates when the animal's head points in a specific direction. HD neurons may be driven by peripheral sensors or, as computational models postulate, internally generated (attractor) mechanisms. We addressed the contributions of stimulus-driven and internally generated activity by recording ensembles of HD neurons in the antero-dorsal thalamic nucleus and the post-subiculum of mice by comparing their activity in various brain states. The temporal correlation structure of HD neurons was preserved during sleep, characterized by a 60°-wide correlated neuronal firing (activity packet), both within and across these two brain structures. During rapid eye movement sleep, the spontaneous drift of the activity packet was similar to that observed during waking and accelerated tenfold during slow-wave sleep. These findings demonstrate that peripheral inputs impinge on an internally organized network, which provides amplification and enhanced precision of the HD signal.",
author = "Petersen, {Peter Christian}",
year = "2015",
doi = "10.1038/nn.3968",
language = "English",
volume = "18",
pages = "569--575",
journal = "Nature Neuroscience",
issn = "1097-6256",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Internally organized mechanisms of the head direction sense

AU - Petersen, Peter Christian

PY - 2015

Y1 - 2015

N2 - The head-direction (HD) system functions as a compass, with member neurons robustly increasing their firing rates when the animal's head points in a specific direction. HD neurons may be driven by peripheral sensors or, as computational models postulate, internally generated (attractor) mechanisms. We addressed the contributions of stimulus-driven and internally generated activity by recording ensembles of HD neurons in the antero-dorsal thalamic nucleus and the post-subiculum of mice by comparing their activity in various brain states. The temporal correlation structure of HD neurons was preserved during sleep, characterized by a 60°-wide correlated neuronal firing (activity packet), both within and across these two brain structures. During rapid eye movement sleep, the spontaneous drift of the activity packet was similar to that observed during waking and accelerated tenfold during slow-wave sleep. These findings demonstrate that peripheral inputs impinge on an internally organized network, which provides amplification and enhanced precision of the HD signal.

AB - The head-direction (HD) system functions as a compass, with member neurons robustly increasing their firing rates when the animal's head points in a specific direction. HD neurons may be driven by peripheral sensors or, as computational models postulate, internally generated (attractor) mechanisms. We addressed the contributions of stimulus-driven and internally generated activity by recording ensembles of HD neurons in the antero-dorsal thalamic nucleus and the post-subiculum of mice by comparing their activity in various brain states. The temporal correlation structure of HD neurons was preserved during sleep, characterized by a 60°-wide correlated neuronal firing (activity packet), both within and across these two brain structures. During rapid eye movement sleep, the spontaneous drift of the activity packet was similar to that observed during waking and accelerated tenfold during slow-wave sleep. These findings demonstrate that peripheral inputs impinge on an internally organized network, which provides amplification and enhanced precision of the HD signal.

U2 - 10.1038/nn.3968

DO - 10.1038/nn.3968

M3 - Journal article

C2 - 25730672

VL - 18

SP - 569

EP - 575

JO - Nature Neuroscience

JF - Nature Neuroscience

SN - 1097-6256

ER -

ID: 138271898