Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells. / Thulesen, S; Nielsen, M; Petersen, T R; Holst Nissen, M; Ødum, Niels; Röpke, C.

In: Cytokine, Vol. 12, No. 6, 2000, p. 751-5.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Thulesen, S, Nielsen, M, Petersen, TR, Holst Nissen, M, Ødum, N & Röpke, C 2000, 'Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.', Cytokine, vol. 12, no. 6, pp. 751-5. https://doi.org/10.1006/cyto.1999.0608

APA

Thulesen, S., Nielsen, M., Petersen, T. R., Holst Nissen, M., Ødum, N., & Röpke, C. (2000). Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells. Cytokine, 12(6), 751-5. https://doi.org/10.1006/cyto.1999.0608

Vancouver

Thulesen S, Nielsen M, Petersen TR, Holst Nissen M, Ødum N, Röpke C. Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells. Cytokine. 2000;12(6):751-5. https://doi.org/10.1006/cyto.1999.0608

Author

Thulesen, S ; Nielsen, M ; Petersen, T R ; Holst Nissen, M ; Ødum, Niels ; Röpke, C. / Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells. In: Cytokine. 2000 ; Vol. 12, No. 6. pp. 751-5.

Bibtex

@article{7a4c7540ba3f11ddae57000ea68e967b,
title = "Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.",
abstract = "The effects of IL-15, as compared to IL-2, on growth of human thymocytes has been evaluated. Expression of comparable amounts of receptor chains was found on IL-2 and IL-15 cultured thymocytes, as well as comparable receptor signalling. However, IL-15 was superior to IL-2 in promoting CD8(+)thymocyte growth, whereas CD4(+)cells proliferated to a higher extent in IL-2 cultures. CD4(+)8(+)and CD4(-)8(-)thymocytes expanded equally well in both culture types.",
author = "S Thulesen and M Nielsen and Petersen, {T R} and {Holst Nissen}, M and Niels {\O}dum and C R{\"o}pke",
note = "Keywords: CD8-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Gene Expression Regulation; Humans; Interleukin-15; Interleukin-2; Receptors, Interleukin-15; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes",
year = "2000",
doi = "10.1006/cyto.1999.0608",
language = "English",
volume = "12",
pages = "751--5",
journal = "Cytokine",
issn = "1043-4666",
publisher = "Academic Press",
number = "6",

}

RIS

TY - JOUR

T1 - Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cells.

AU - Thulesen, S

AU - Nielsen, M

AU - Petersen, T R

AU - Holst Nissen, M

AU - Ødum, Niels

AU - Röpke, C

N1 - Keywords: CD8-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Gene Expression Regulation; Humans; Interleukin-15; Interleukin-2; Receptors, Interleukin-15; Receptors, Interleukin-2; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes

PY - 2000

Y1 - 2000

N2 - The effects of IL-15, as compared to IL-2, on growth of human thymocytes has been evaluated. Expression of comparable amounts of receptor chains was found on IL-2 and IL-15 cultured thymocytes, as well as comparable receptor signalling. However, IL-15 was superior to IL-2 in promoting CD8(+)thymocyte growth, whereas CD4(+)cells proliferated to a higher extent in IL-2 cultures. CD4(+)8(+)and CD4(-)8(-)thymocytes expanded equally well in both culture types.

AB - The effects of IL-15, as compared to IL-2, on growth of human thymocytes has been evaluated. Expression of comparable amounts of receptor chains was found on IL-2 and IL-15 cultured thymocytes, as well as comparable receptor signalling. However, IL-15 was superior to IL-2 in promoting CD8(+)thymocyte growth, whereas CD4(+)cells proliferated to a higher extent in IL-2 cultures. CD4(+)8(+)and CD4(-)8(-)thymocytes expanded equally well in both culture types.

U2 - 10.1006/cyto.1999.0608

DO - 10.1006/cyto.1999.0608

M3 - Journal article

C2 - 10843758

VL - 12

SP - 751

EP - 755

JO - Cytokine

JF - Cytokine

SN - 1043-4666

IS - 6

ER -

ID: 8747510