In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet. / Strube, Mikael Lenz; Jensen, Tim Kåre; Meyer, Anne S.; Boye, Mette.

In: A M B Express, 2015.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Strube, ML, Jensen, TK, Meyer, AS & Boye, M 2015, 'In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet', A M B Express. https://doi.org/10.1186/s13568-015-0152-1

APA

Strube, M. L., Jensen, T. K., Meyer, A. S., & Boye, M. (2015). In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet. A M B Express. https://doi.org/10.1186/s13568-015-0152-1

Vancouver

Strube ML, Jensen TK, Meyer AS, Boye M. In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet. A M B Express. 2015. https://doi.org/10.1186/s13568-015-0152-1

Author

Strube, Mikael Lenz ; Jensen, Tim Kåre ; Meyer, Anne S. ; Boye, Mette. / In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet. In: A M B Express. 2015.

Bibtex

@article{3f492d8f2b2e44a58e4071d60d123b1b,
title = "In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet",
abstract = "Prebiotics may be efficient for prevention of intestinal infections in humans and animals by increasing the levels of beneficial bacteria and thereby improving gut health. Using purified prebiotics may however not be cost-effective in the livestock production industry. Instead, prebiotic fibres may be released directly in the gastro-intestinal tract by feeding enzymes with a suitable substrate and allowing the prebiotics to be produced in situ. Using low doses, 0.03 % enzyme-to-substrate ratio, of the enzymes pectin lyase and polygalacturonase in combination with potato pulp, a low-value industrial by-product, we show that high molecular weight galacto-rhamnogalacturonan can be solubilized in the stomach of weaning piglets. The release of this fiber is in the order of 22–38 % of the theoretical amount, achieved within 20 min. The catalysis takes place mainly in the stomach of the animal and is then followed by distribution through the small intestines. To our knowledge, this is the first paper describing targeted production of prebiotics in an animal model.",
author = "Strube, {Mikael Lenz} and Jensen, {Tim K{\aa}re} and Meyer, {Anne S.} and Mette Boye",
year = "2015",
doi = "10.1186/s13568-015-0152-1",
language = "English",
journal = "AMB Express",
issn = "2191-0855",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - In situ prebiotics: enzymatic release of galacto-rhamnogalacturonan from potato pulp in vivo in the gastrointestinal tract of the weaning piglet

AU - Strube, Mikael Lenz

AU - Jensen, Tim Kåre

AU - Meyer, Anne S.

AU - Boye, Mette

PY - 2015

Y1 - 2015

N2 - Prebiotics may be efficient for prevention of intestinal infections in humans and animals by increasing the levels of beneficial bacteria and thereby improving gut health. Using purified prebiotics may however not be cost-effective in the livestock production industry. Instead, prebiotic fibres may be released directly in the gastro-intestinal tract by feeding enzymes with a suitable substrate and allowing the prebiotics to be produced in situ. Using low doses, 0.03 % enzyme-to-substrate ratio, of the enzymes pectin lyase and polygalacturonase in combination with potato pulp, a low-value industrial by-product, we show that high molecular weight galacto-rhamnogalacturonan can be solubilized in the stomach of weaning piglets. The release of this fiber is in the order of 22–38 % of the theoretical amount, achieved within 20 min. The catalysis takes place mainly in the stomach of the animal and is then followed by distribution through the small intestines. To our knowledge, this is the first paper describing targeted production of prebiotics in an animal model.

AB - Prebiotics may be efficient for prevention of intestinal infections in humans and animals by increasing the levels of beneficial bacteria and thereby improving gut health. Using purified prebiotics may however not be cost-effective in the livestock production industry. Instead, prebiotic fibres may be released directly in the gastro-intestinal tract by feeding enzymes with a suitable substrate and allowing the prebiotics to be produced in situ. Using low doses, 0.03 % enzyme-to-substrate ratio, of the enzymes pectin lyase and polygalacturonase in combination with potato pulp, a low-value industrial by-product, we show that high molecular weight galacto-rhamnogalacturonan can be solubilized in the stomach of weaning piglets. The release of this fiber is in the order of 22–38 % of the theoretical amount, achieved within 20 min. The catalysis takes place mainly in the stomach of the animal and is then followed by distribution through the small intestines. To our knowledge, this is the first paper describing targeted production of prebiotics in an animal model.

U2 - 10.1186/s13568-015-0152-1

DO - 10.1186/s13568-015-0152-1

M3 - Journal article

C2 - 26475351

JO - AMB Express

JF - AMB Express

SN - 2191-0855

ER -

ID: 339250711