Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Metformin has been reported to reduce a-dicarbonyls, which are known to contribute to diabetic complications. It is unclear whether this is due to direct quenching of a-dicarbonyls or to an improvement in glycemic control. We therefore compared the effects of metformin versus repaglinide, an antihyperglycemic agent with an insulin-secreting mechanism, on the levels of the a-dicarbonyl 3-deoxyglucosone (3DG).
Original language | English |
---|---|
Journal | European Journal of Endocrinology |
Volume | 164 |
Issue number | 3 |
Pages (from-to) | 371-9 |
Number of pages | 9 |
ISSN | 0804-4643 |
DOIs | |
Publication status | Published - 2011 |
- Carbamates, Confidence Intervals, Deoxyglucose, Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Metformin, Piperidines
Research areas
ID: 35312496