Important options available--from start to finish--for translating proteomics results to clinical chemistry

Research output: Contribution to journal › Review › Research › peer-review

Standard

Important options available--from start to finish--for translating proteomics results to clinical chemistry. / Heegaard, Niels H H; Østergaard, Ole; Bahl, Justyna M C; Overgaard, Martin; Beck, Hans C; Rasmussen, Lars Melholt; Larsen, Martin Røssel.

In: Proteomics - Clinical Applications, Vol. 9, No. 1-2, 2015, p. 235-252.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Heegaard, NHH, Østergaard, O, Bahl, JMC, Overgaard, M, Beck, HC, Rasmussen, LM & Larsen, MR 2015, 'Important options available--from start to finish--for translating proteomics results to clinical chemistry', Proteomics - Clinical Applications, vol. 9, no. 1-2, pp. 235-252. https://doi.org/10.1002/prca.201400137

APA

Heegaard, N. H. H., Østergaard, O., Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M., & Larsen, M. R. (2015). Important options available--from start to finish--for translating proteomics results to clinical chemistry. Proteomics - Clinical Applications, 9(1-2), 235-252. https://doi.org/10.1002/prca.201400137

Vancouver

Heegaard NHH, Østergaard O, Bahl JMC, Overgaard M, Beck HC, Rasmussen LM et al. Important options available--from start to finish--for translating proteomics results to clinical chemistry. Proteomics - Clinical Applications. 2015;9(1-2):235-252. https://doi.org/10.1002/prca.201400137

Author

Heegaard, Niels H H ; Østergaard, Ole ; Bahl, Justyna M C ; Overgaard, Martin ; Beck, Hans C ; Rasmussen, Lars Melholt ; Larsen, Martin Røssel. / Important options available--from start to finish--for translating proteomics results to clinical chemistry. In: Proteomics - Clinical Applications. 2015 ; Vol. 9, No. 1-2. pp. 235-252.

Bibtex

@article{68eaaa1f3d5f449390bee4e4cd5b29e5,
title = "Important options available--from start to finish--for translating proteomics results to clinical chemistry",
abstract = "In the realm of clinical chemistry, the field of clinical proteomics, that is, the application of proteomic methods for understanding mechanisms and enabling diagnosis, prediction, measurement of activity, and treatment response in disease, is first and foremost a discovery and research tool that feeds assay development downstream. Putative new assay candidates generated by proteomics discovery projects compete with well-established assays with known indications, well-described performance, and of known value in specific clinical settings. Careful attention to the many options available in the design, execution, and interpretation of clinical proteomics studies is thus necessary for translation into clinical practice. We here review and discuss important options associated with clinical proteomics endeavors stretching from the planning phases to the final use in clinical chemistry. ",
keywords = "Biomarkers/analysis, Clinical Medicine, Humans, Proteome/analysis, Proteomics/methods",
author = "Heegaard, {Niels H H} and Ole {\O}stergaard and Bahl, {Justyna M C} and Martin Overgaard and Beck, {Hans C} and Rasmussen, {Lars Melholt} and Larsen, {Martin R{\o}ssel}",
note = "{\textcopyright} 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2015",
doi = "10.1002/prca.201400137",
language = "English",
volume = "9",
pages = "235--252",
journal = "Proteomics - Clinical Applications",
issn = "1862-8346",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "1-2",

}

RIS

TY - JOUR

T1 - Important options available--from start to finish--for translating proteomics results to clinical chemistry

AU - Heegaard, Niels H H

AU - Østergaard, Ole

AU - Bahl, Justyna M C

AU - Overgaard, Martin

AU - Beck, Hans C

AU - Rasmussen, Lars Melholt

AU - Larsen, Martin Røssel

N1 - © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2015

Y1 - 2015

N2 - In the realm of clinical chemistry, the field of clinical proteomics, that is, the application of proteomic methods for understanding mechanisms and enabling diagnosis, prediction, measurement of activity, and treatment response in disease, is first and foremost a discovery and research tool that feeds assay development downstream. Putative new assay candidates generated by proteomics discovery projects compete with well-established assays with known indications, well-described performance, and of known value in specific clinical settings. Careful attention to the many options available in the design, execution, and interpretation of clinical proteomics studies is thus necessary for translation into clinical practice. We here review and discuss important options associated with clinical proteomics endeavors stretching from the planning phases to the final use in clinical chemistry.

AB - In the realm of clinical chemistry, the field of clinical proteomics, that is, the application of proteomic methods for understanding mechanisms and enabling diagnosis, prediction, measurement of activity, and treatment response in disease, is first and foremost a discovery and research tool that feeds assay development downstream. Putative new assay candidates generated by proteomics discovery projects compete with well-established assays with known indications, well-described performance, and of known value in specific clinical settings. Careful attention to the many options available in the design, execution, and interpretation of clinical proteomics studies is thus necessary for translation into clinical practice. We here review and discuss important options associated with clinical proteomics endeavors stretching from the planning phases to the final use in clinical chemistry.

KW - Biomarkers/analysis

KW - Clinical Medicine

KW - Humans

KW - Proteome/analysis

KW - Proteomics/methods

U2 - 10.1002/prca.201400137

DO - 10.1002/prca.201400137

M3 - Review

C2 - 25472910

VL - 9

SP - 235

EP - 252

JO - Proteomics - Clinical Applications

JF - Proteomics - Clinical Applications

SN - 1862-8346

IS - 1-2

ER -

ID: 210474533