Health-Related Quality of Life and Physical Function in Individuals with Parkinson's Disease after a Multidisciplinary Rehabilitation Regimen-A Prospective Cohort Feasibility Study
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- Health-Related Quality of Life and Physical Function in Individuals with Parkinson’s Disease after a Multidisciplinary Rehabilitation Regimen—A Prospective Cohort Feasibility Study
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Parkinson's disease (PD) is a neurodegenerative disease and a multidisciplinary approach to rehabilitation has been suggested as the best clinical practice. However, very few studies have investigated the long-term effects of a multidisciplinary rehabilitation approach, particularly regarding whether this can slow the progression of PD. The purpose was to investigate the short- and long-term effect of a 2-week multidisciplinary rehabilitation regimen on the PD-related decline in health-related quality of life (HRQOL), mobility, and muscle function. Individuals with PD (IPD) participated in a 2-week inpatient multidisciplinary rehabilitation regimen that focused on improving HRQOL, mobility, and muscle function. Data from the primary outcome: HRQOL (Parkinson's Disease Questionnaire 39, PDQ-39), secondary outcomes: handgrip strength, Timed-up and Go (TUG), Hospital Anxiety and Depression Scale (HADS), and Falls Efficacy Scale-International (FES-I) were compared at pre-visitation, before and after the 2-week regimen, and again at 4 and 10 months follow-up. In total, 224 patients with PD were included. There were short-term improvements in all outcomes. PDQ-39 was maintained at the same level as pre-visitation after 10 months follow-up. A 2-week multidisciplinary rehabilitation regimen improved short-term mobility, muscle function, and HRQOL in individuals with Parkinson's disease. HRQOL was maintained after 10 months demonstrating long-term effects.
Original language | English |
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Article number | 7668 |
Journal | International Journal of Environmental Research and Public Health |
Volume | 17 |
Issue number | 20 |
Number of pages | 13 |
ISSN | 1661-7827 |
DOIs | |
Publication status | Published - Jan 2020 |
- multidisciplinary rehabilitation, health-related quality of life, physical function, Parkinson’, s disease, COGNITIVE IMPAIRMENT, EXERCISE, PEOPLE, METAANALYSIS, TERM
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