Glucagon like peptide-1-induced glucose metabolism in differentiated human muscle satellite cells is attenuated by hyperglycemia
Research output: Contribution to journal › Journal article › Research › peer-review
Glucagon like peptide-1 (GLP-1) stimulates insulin secretion from the pancreas but also has extra-pancreatic effects. GLP-1 may stimulate glucose uptake in cultured muscle cells but the mechanism is not clearly defined. Furthermore, while the pancreatic effects of GLP-1 are glucose-dependent, the glucose-dependency of its extra-pancreatic effects has not been examined.
Original language | English |
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Journal | P L o S One |
Volume | 7 |
Issue number | 8 |
Pages (from-to) | e44284 |
ISSN | 1932-6203 |
DOIs | |
Publication status | Published - 2012 |
- Cell Differentiation, Cell Proliferation, Cells, Cultured, Glucagon-Like Peptide 1, Glucose, Glycogen, Humans, Hyperglycemia, Insulin, Male, Receptors, Glucagon, Satellite Cells, Skeletal Muscle, Signal Transduction, Young Adult
Research areas
ID: 48551688