Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho. / Narvestad-Bøttger, Helene; Winther-Larsen, Anne; Haugbølle Bjerre, Jens; Dziegiel, Morten Hanefeld; Hansen, Anne Todsen; Hasle, Henrik.

In: Journal of Pediatric Hematology/Oncology, Vol. 46, No. 1, 01.01.2024, p. e111-e114.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Narvestad-Bøttger, H, Winther-Larsen, A, Haugbølle Bjerre, J, Dziegiel, MH, Hansen, AT & Hasle, H 2024, 'Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho', Journal of Pediatric Hematology/Oncology, vol. 46, no. 1, pp. e111-e114. https://doi.org/10.1097/MPH.0000000000002790

APA

Narvestad-Bøttger, H., Winther-Larsen, A., Haugbølle Bjerre, J., Dziegiel, M. H., Hansen, A. T., & Hasle, H. (2024). Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho. Journal of Pediatric Hematology/Oncology, 46(1), e111-e114. https://doi.org/10.1097/MPH.0000000000002790

Vancouver

Narvestad-Bøttger H, Winther-Larsen A, Haugbølle Bjerre J, Dziegiel MH, Hansen AT, Hasle H. Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho. Journal of Pediatric Hematology/Oncology. 2024 Jan 1;46(1):e111-e114. https://doi.org/10.1097/MPH.0000000000002790

Author

Narvestad-Bøttger, Helene ; Winther-Larsen, Anne ; Haugbølle Bjerre, Jens ; Dziegiel, Morten Hanefeld ; Hansen, Anne Todsen ; Hasle, Henrik. / Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho. In: Journal of Pediatric Hematology/Oncology. 2024 ; Vol. 46, No. 1. pp. e111-e114.

Bibtex

@article{c13248c91acc4324ba5b1669d7253a1b,

title = "Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho",

abstract = "BACKGROUND: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions.OBSERVATIONS: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×10 9 /L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count.CONCLUSIONS: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.",

keywords = "Male, Humans, Child, Preschool, Reticulocytosis, Splenectomy/adverse effects, Hemoglobins, Abnormal, Erythrocyte Inclusions",

author = "Helene Narvestad-B{\o}ttger and Anne Winther-Larsen and {Haugb{\o}lle Bjerre}, Jens and Dziegiel, {Morten Hanefeld} and Hansen, {Anne Todsen} and Henrik Hasle",

year = "2024",

month = jan,

day = "1",

doi = "10.1097/MPH.0000000000002790",

language = "English",

volume = "46",

pages = "e111--e114",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams & Wilkins",

number = "1",

}

RIS

TY - JOUR

T1 - Extreme Reticulocytosis After Splenectomy in a Patient With Hemoglobin Mizuho

AU - Narvestad-Bøttger, Helene

AU - Winther-Larsen, Anne

AU - Haugbølle Bjerre, Jens

AU - Dziegiel, Morten Hanefeld

AU - Hansen, Anne Todsen

AU - Hasle, Henrik

PY - 2024/1/1

Y1 - 2024/1/1

N2 - BACKGROUND: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions.OBSERVATIONS: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×10 9 /L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count.CONCLUSIONS: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.

AB - BACKGROUND: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions.OBSERVATIONS: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×10 9 /L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count.CONCLUSIONS: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.

KW - Male

KW - Humans

KW - Child, Preschool

KW - Reticulocytosis

KW - Splenectomy/adverse effects

KW - Hemoglobins, Abnormal

KW - Erythrocyte Inclusions

U2 - 10.1097/MPH.0000000000002790

DO - 10.1097/MPH.0000000000002790

M3 - Journal article

C2 - 38011049

VL - 46

SP - e111-e114

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

IS - 1

ER -

ID: 398644775

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