Extravasation of chemotherapy
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Extravasation of chemotherapy. / Langer, Seppo W.
In: Current Oncology Reports, Vol. 12, No. 4, 07.2010, p. 242-6.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Extravasation of chemotherapy
AU - Langer, Seppo W
PY - 2010/7
Y1 - 2010/7
N2 - Extravasation of chemotherapy is a feared complication of anticancer therapy. The accidental leakage of cytostatic agents into the perivascular tissues may have devastating short-term and long-term consequences for patients. In recent years, the increased focus on chemotherapy extravasation has led to the development of international guidelines that have proven useful tools in daily clinical practice. Moreover, the tissue destruction in one of the most dreaded types of extravasation (ie, anthracycline extravasation) now can effectively be prevented with a specific antidote, dexrazoxane.
AB - Extravasation of chemotherapy is a feared complication of anticancer therapy. The accidental leakage of cytostatic agents into the perivascular tissues may have devastating short-term and long-term consequences for patients. In recent years, the increased focus on chemotherapy extravasation has led to the development of international guidelines that have proven useful tools in daily clinical practice. Moreover, the tissue destruction in one of the most dreaded types of extravasation (ie, anthracycline extravasation) now can effectively be prevented with a specific antidote, dexrazoxane.
KW - Anthracyclines/adverse effects
KW - Drug-Related Side Effects and Adverse Reactions
KW - Extravasation of Diagnostic and Therapeutic Materials/prevention & control
KW - Humans
KW - Pharmaceutical Preparations/administration & dosage
KW - Razoxane/therapeutic use
KW - Treatment Outcome
U2 - 10.1007/s11912-010-0110-7
DO - 10.1007/s11912-010-0110-7
M3 - Review
C2 - 20480268
VL - 12
SP - 242
EP - 246
JO - Current Oncology Reports
JF - Current Oncology Reports
SN - 1523-3790
IS - 4
ER -
ID: 247891221