Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity
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Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity. / Andersen, G; Wegner, L; Yanagisawa, K; Rose, C S; Lin, J; Glümer, C; Drivsholm, T; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Spiegelman, B M; Pedersen, O.
In: Journal of Medical Genetics, Vol. 42, No. 5, 01.05.2005, p. 402-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity
AU - Andersen, G
AU - Wegner, L
AU - Yanagisawa, K
AU - Rose, C S
AU - Lin, J
AU - Glümer, C
AU - Drivsholm, T
AU - Borch-Johnsen, K
AU - Jørgensen, T
AU - Hansen, T
AU - Spiegelman, B M
AU - Pedersen, O
PY - 2005/5/1
Y1 - 2005/5/1
N2 - Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
AB - Peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) is a recently identified homologue of the tissue specific coactivator PGC-1alpha, a coactivator of transcription factors such as the peroxisome proliferators activated receptors and nuclear respiratory factors. PGC-1alpha is involved in adipogenesis, mitochondrial biogenesis, fatty acid beta oxidation, and hepatic gluconeogenesis.
KW - Aged
KW - Carrier Proteins
KW - DNA Mutational Analysis
KW - Denmark
KW - Diabetes Mellitus, Type 2
KW - Gene Frequency
KW - Genetic Testing
KW - Genetic Variation
KW - Genotype
KW - Glucose
KW - Humans
KW - Linkage Disequilibrium
KW - Middle Aged
KW - Mutation
KW - Obesity
U2 - 10.1136/jmg.2004.026278
DO - 10.1136/jmg.2004.026278
M3 - Journal article
C2 - 15863669
VL - 42
SP - 402
EP - 407
JO - Journal of Medical Genetics
JF - Journal of Medical Genetics
SN - 0022-2593
IS - 5
ER -
ID: 33030532