Evaluation of Analytical Performance Assisted by Total Error Criteria of a Commercial Enzyme Immunometric Assay for Canine Serum Thyrotropin
Research output: Contribution to journal › Review › Research › peer-review
Standard
Evaluation of Analytical Performance Assisted by Total Error Criteria of a Commercial Enzyme Immunometric Assay for Canine Serum Thyrotropin. / Jensen, Asger Lundorff; Iversen, Lars; Høier, Rene.
In: Veterinary Clinical Pathology, Vol. 28, No. 2, 1999, p. 53+56.Research output: Contribution to journal › Review › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Evaluation of Analytical Performance Assisted by Total Error Criteria of a Commercial Enzyme Immunometric Assay for Canine Serum Thyrotropin
AU - Jensen, Asger Lundorff
AU - Iversen, Lars
AU - Høier, Rene
PY - 1999
Y1 - 1999
N2 - The aim of the present study was to evaluate analytical performance using total error criteria of a commercial enzyme immunometric assay for the determination of endogenous canine thyrotropin (TSH). The allowable total error for this assay (22.6%) was estimated using previously reported data on biological variation. Inaccuracy and imprecision of the assay (0% and 5.7% for the low control material; 6.8% and 3.0% for the high control material) were estimated by measuring the same lot of control material for 21 consecutive weeks, during which time the assay was considered stable and in control Analytical performance was assessed using a MEDx chart, a graphical tool for comparing inaccuracy and imprecision, with an analytical quality requirement stated in the form of allowable total error. The results of the present study showed that the canine TSH assay had good to excellent analytical performance.
AB - The aim of the present study was to evaluate analytical performance using total error criteria of a commercial enzyme immunometric assay for the determination of endogenous canine thyrotropin (TSH). The allowable total error for this assay (22.6%) was estimated using previously reported data on biological variation. Inaccuracy and imprecision of the assay (0% and 5.7% for the low control material; 6.8% and 3.0% for the high control material) were estimated by measuring the same lot of control material for 21 consecutive weeks, during which time the assay was considered stable and in control Analytical performance was assessed using a MEDx chart, a graphical tool for comparing inaccuracy and imprecision, with an analytical quality requirement stated in the form of allowable total error. The results of the present study showed that the canine TSH assay had good to excellent analytical performance.
KW - Accuracy
KW - Dog
KW - Hypothyroidism
KW - Precision
KW - Quality goals
UR - http://www.scopus.com/inward/record.url?scp=0033471676&partnerID=8YFLogxK
U2 - 10.1111/j.1939-165X.1999.tb01045.x
DO - 10.1111/j.1939-165X.1999.tb01045.x
M3 - Review
AN - SCOPUS:0033471676
VL - 28
SP - 53+56
JO - Veterinary Clinical Pathology
JF - Veterinary Clinical Pathology
SN - 0275-6382
IS - 2
ER -
ID: 255558811