Efficient cell culture system for hepatitis C virus genotype 2B: Patent #: 8,663,653

Research output: Patent

Standard

Efficient cell culture system for hepatitis C virus genotype 2B : Patent #: 8,663,653 . / Gottwein, Judith Margarete (Inventor); Knudsen, Maria Lisa (Inventor); Scheel, Troels Kasper Hoyer (Inventor); Bukh, Jens (Inventor).

Patent No.: WO2010/017818. Mar 31, 2014.

Research output: Patent

Harvard

Gottwein, JM, Knudsen, ML, Scheel, TKH & Bukh, J Mar. 31 2014, Efficient cell culture system for hepatitis C virus genotype 2B: Patent #: 8,663,653 , Patent No. WO2010/017818.

APA

Gottwein, J. M., Knudsen, M. L., Scheel, T. K. H., & Bukh, J. (2014). Efficient cell culture system for hepatitis C virus genotype 2B: Patent #: 8,663,653 . (Patent No. WO2010/017818).

Vancouver

Gottwein JM, Knudsen ML, Scheel TKH, Bukh J, inventors. Efficient cell culture system for hepatitis C virus genotype 2B: Patent #: 8,663,653 . WO2010/017818. 2014 Mar 31.

Author

Gottwein, Judith Margarete (Inventor) ; Knudsen, Maria Lisa (Inventor) ; Scheel, Troels Kasper Hoyer (Inventor) ; Bukh, Jens (Inventor). / Efficient cell culture system for hepatitis C virus genotype 2B : Patent #: 8,663,653 . Patent No.: WO2010/017818. Mar 31, 2014.

Bibtex

@misc{f58b685769cf4df885ffca2d50607cba,
title = "Efficient cell culture system for hepatitis C virus genotype 2B: Patent #: 8,663,653 ",
abstract = "The present inventors developed hepatitis C virus 2b/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and the complete NS2 were replaced by the corresponding genes of the genotype 2b reference strain J8. Sequence analysis of recovered 2b/2a recombinants from 2 transfection experiments revealed that 2b/2a was genetically stable. Conclusion: The developed 2b/2a viruses provide a robust in vitro tool for research in HCV genotype 2b, including vaccine studies and functional analysis.",
author = "Gottwein, {Judith Margarete} and Knudsen, {Maria Lisa} and Scheel, {Troels Kasper Hoyer} and Jens Bukh",
year = "2014",
month = mar,
day = "31",
language = "English",
type = "Patent",
note = "WO2010/017818; A61K 39/12 (20060101); A61K 39/29 (20060101); C12N 1/20 (20060101); C12N 5/071 (20100101); C12N 15/00 (20060101); C12Q 1/70 (20060101)",

}

RIS

TY - PAT

T1 - Efficient cell culture system for hepatitis C virus genotype 2B

T2 - Patent #: 8,663,653

AU - Gottwein, Judith Margarete

AU - Knudsen, Maria Lisa

AU - Scheel, Troels Kasper Hoyer

AU - Bukh, Jens

PY - 2014/3/31

Y1 - 2014/3/31

N2 - The present inventors developed hepatitis C virus 2b/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and the complete NS2 were replaced by the corresponding genes of the genotype 2b reference strain J8. Sequence analysis of recovered 2b/2a recombinants from 2 transfection experiments revealed that 2b/2a was genetically stable. Conclusion: The developed 2b/2a viruses provide a robust in vitro tool for research in HCV genotype 2b, including vaccine studies and functional analysis.

AB - The present inventors developed hepatitis C virus 2b/2a intergenotypic recombinants in which the JFH1 structural genes (Core, E1 and E2), p7 and the complete NS2 were replaced by the corresponding genes of the genotype 2b reference strain J8. Sequence analysis of recovered 2b/2a recombinants from 2 transfection experiments revealed that 2b/2a was genetically stable. Conclusion: The developed 2b/2a viruses provide a robust in vitro tool for research in HCV genotype 2b, including vaccine studies and functional analysis.

M3 - Patent

M1 - WO2010/017818

Y2 - 2010/02/18

ER -

ID: 140392319