Effects of insulin detemir and NPH insulin on renal handling of sodium, fluid retention and weight in type 2 diabetic patients
Research output: Contribution to journal › Journal article › Research › peer-review
In type 2 diabetic patients, insulin detemir (B29Lys(ε-tetradecanoyl),desB30 human insulin) induces less weight gain than NPH insulin. Due to the proposed reduction of tubular action by insulin detemir, type 2 diabetic patients should have increased urinary sodium excretion, thereby reducing extracellular volume and body weight when changed from NPH insulin to insulin detemir.
| Original language | English |
|---|---|
| Journal | Diabetologia |
| Volume | 55 |
| Issue number | 1 |
| Pages (from-to) | 46-50 |
| Number of pages | 5 |
| ISSN | 0012-186X |
| DOIs | |
| Publication status | Published - 2012 |
ID: 48445263