Duration of wound fluid secretion from chronic venous leg ulcers is critical for interleukin-1α, interleukin-1β, interleukin-8 levels and fibroblast activation
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Duration of wound fluid secretion from chronic venous leg ulcers is critical for interleukin-1α, interleukin-1β, interleukin-8 levels and fibroblast activation. / Zillmer, Rikke; Trøstrup, Hannah; Karlsmark, Tonny; Ifversen, Peter; Ågren, Sven Per Magnus.
In: Archives of Dermatological Research, Vol. 303, No. 8, 2011, p. 601-6.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Duration of wound fluid secretion from chronic venous leg ulcers is critical for interleukin-1α, interleukin-1β, interleukin-8 levels and fibroblast activation
AU - Zillmer, Rikke
AU - Trøstrup, Hannah
AU - Karlsmark, Tonny
AU - Ifversen, Peter
AU - Ågren, Sven Per Magnus
PY - 2011
Y1 - 2011
N2 - Wound fluid collected from chronic wounds may be used as a simple gauge of the processes taking place in the tissue. There is lack of information on the optimal conditions for wound fluid procurement. We have studied possible diurnal variations and duration of wound fluid accumulation using retentive hydrophobic foam on the levels of prototypic cytokines [interleukin (IL)-1a, IL-1ß], a chemokine (IL-8) and proteinases [matrix metalloproteinase (MMP)-9] in 23 chronic venous leg ulcer patients. Bioactivity of 1 and 24 h wound fluids, and serum was also compared. There were no significant temporal changes in the levels of the above-mentioned four proteins, when comparing three consecutive 8-h intervals starting from 0800 that in turn did not differ significantly with the 24-h collection levels. IL-1a, IL-1ß and IL-8 levels were higher (p
AB - Wound fluid collected from chronic wounds may be used as a simple gauge of the processes taking place in the tissue. There is lack of information on the optimal conditions for wound fluid procurement. We have studied possible diurnal variations and duration of wound fluid accumulation using retentive hydrophobic foam on the levels of prototypic cytokines [interleukin (IL)-1a, IL-1ß], a chemokine (IL-8) and proteinases [matrix metalloproteinase (MMP)-9] in 23 chronic venous leg ulcer patients. Bioactivity of 1 and 24 h wound fluids, and serum was also compared. There were no significant temporal changes in the levels of the above-mentioned four proteins, when comparing three consecutive 8-h intervals starting from 0800 that in turn did not differ significantly with the 24-h collection levels. IL-1a, IL-1ß and IL-8 levels were higher (p
U2 - http://dx.doi.org/10.1007/s00403-011-1164-6
DO - http://dx.doi.org/10.1007/s00403-011-1164-6
M3 - Journal article
VL - 303
SP - 601
EP - 606
JO - Archiv für Dermatologische Forschung
JF - Archiv für Dermatologische Forschung
SN - 0340-3696
IS - 8
ER -
ID: 40168384