Difusión simultánea de inositol y manitol en cerebro de rata.
Research output: Contribution to journal › Journal article › Research › peer-review
The diffusion of both inositol and mannitol has been determined simultaneously by the integral bolus method in rat brain. The permeability constant (Kin) of inositol averaged 0.27 +/- 0.02 ml X (100 g)-1 X min-1 or 4 X 10(-7) cm X s-1 at a cerebral capillary surface area of 100 cm2 x g-1. The permeability of mannitol was 0.08 +/- 0.01 ml X (100 g)-1. min-1 or 1 X 10(-7) cm X s-1. Neither glucose nor galactose affected the inositol permeability. Hypoglycemia increased somewhat the Km value for mannitol. The basal ganglia showed an increase Km for both substrates as compared with those obtained for cortex, temporal and parietal tissues.
Translated title of the contribution | Simultaneous diffusion of inositol and mannitol in the rat brain |
---|---|
Original language | Spanish |
Journal | Revista española de fisiología |
Volume | 38 |
Issue number | 3 |
Pages (from-to) | 317-9 |
Number of pages | 2 |
ISSN | 0034-9402 |
Publication status | Published - 1982 |
Externally published | Yes |
ID: 14946743