Detection of arousals in Parkinson's disease patients
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Detection of arousals in Parkinson's disease patients. / Sørensen, Gertrud Laura; Kempfner, Jacob; Jennum, Poul; Sorensen, Helge B D.
In: I E E E Engineering in Medicine and Biology Society. Conference Proceedings, Vol. 2011, 2011, p. 2764-7.Research output: Contribution to journal › Conference article › Research › peer-review
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TY - GEN
T1 - Detection of arousals in Parkinson's disease patients
AU - Sørensen, Gertrud Laura
AU - Kempfner, Jacob
AU - Jennum, Poul
AU - Sorensen, Helge B D
PY - 2011
Y1 - 2011
N2 - Arousal from sleep are short awakenings, which can be identified in the EEG as an abrupt change in frequency. Arousals can occur in all sleep stages and the number and frequency increase with age. Frequent arousals during sleep results in sleep fragmentation and is associated with daytime sleepiness. Manual scoring of arousals is time-consuming and the inter-score agreement is highly varying especially for patients with sleep related disorders. The aim of this study was to design an arousal detection algorithm capable of detecting arousals from sleep, in both non-REM and REM sleep in patients suffering from Parkinson's disease (PD). The proposed algorithm uses features from EEG, EMG and the manual sleep stage scoring as input to a feed-forward artificial neural network (ANN). The performance of the algorithm has been assessed using polysomnographic (PSG) recordings from a total of 8 patients diagnosed with PD. The performance of the algorithm was validated using the leave-one-out method resulting in a sensitivity of 89.8 % and a positive predictive value (PPV) of 88.8 %. This result is high compared to previous presented arousal detection algorithms.
AB - Arousal from sleep are short awakenings, which can be identified in the EEG as an abrupt change in frequency. Arousals can occur in all sleep stages and the number and frequency increase with age. Frequent arousals during sleep results in sleep fragmentation and is associated with daytime sleepiness. Manual scoring of arousals is time-consuming and the inter-score agreement is highly varying especially for patients with sleep related disorders. The aim of this study was to design an arousal detection algorithm capable of detecting arousals from sleep, in both non-REM and REM sleep in patients suffering from Parkinson's disease (PD). The proposed algorithm uses features from EEG, EMG and the manual sleep stage scoring as input to a feed-forward artificial neural network (ANN). The performance of the algorithm has been assessed using polysomnographic (PSG) recordings from a total of 8 patients diagnosed with PD. The performance of the algorithm was validated using the leave-one-out method resulting in a sensitivity of 89.8 % and a positive predictive value (PPV) of 88.8 %. This result is high compared to previous presented arousal detection algorithms.
U2 - 10.1109/IEMBS.2011.6090757
DO - 10.1109/IEMBS.2011.6090757
M3 - Conference article
VL - 2011
SP - 2764
EP - 2767
JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SN - 0589-1019
ER -
ID: 40162679