Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria. / Megnekou, Rosette; Staalsoe, Trine; Hviid, Lars.

In: Malaria Journal, Vol. 12, No. 1, 01.11.2013, p. 387.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Megnekou, R, Staalsoe, T & Hviid, L 2013, 'Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria', Malaria Journal, vol. 12, no. 1, pp. 387. https://doi.org/10.1186/1475-2875-12-387

APA

Megnekou, R., Staalsoe, T., & Hviid, L. (2013). Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria. Malaria Journal, 12(1), 387. https://doi.org/10.1186/1475-2875-12-387

Vancouver

Megnekou R, Staalsoe T, Hviid L. Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria. Malaria Journal. 2013 Nov 1;12(1):387. https://doi.org/10.1186/1475-2875-12-387

Author

Megnekou, Rosette ; Staalsoe, Trine ; Hviid, Lars. / Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria. In: Malaria Journal. 2013 ; Vol. 12, No. 1. pp. 387.

Bibtex

@article{e58af3daab0e4ca5bc3f4fee794bda2b,
title = "Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria",
abstract = "During childhood, residents of areas with stable transmission of Plasmodium falciparum parasites acquire substantial protective immunity to malaria, and adults therefore rarely experience clinical disease episodes. However, susceptibility to infection reappears in pregnant women, particularly primigravidae. This is due to appearance of antigenic parasite variants that are restricted to pregnancy. Variant-specific immunity also governs pregnancy-associated recrudescence of Plasmodium berghei infection in pregnant mice. Pregnancy-related changes in the plasma cytokine levels of mice with immunity acquired prior to first pregnancy have not been studied in detail previously, and were the topic of the present study.",
author = "Rosette Megnekou and Trine Staalsoe and Lars Hviid",
year = "2013",
month = nov,
day = "1",
doi = "10.1186/1475-2875-12-387",
language = "English",
volume = "12",
pages = "387",
journal = "Malaria Journal",
issn = "1475-2875",
publisher = "BioMed Central",
number = "1",

}

RIS

TY - JOUR

T1 - Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

AU - Megnekou, Rosette

AU - Staalsoe, Trine

AU - Hviid, Lars

PY - 2013/11/1

Y1 - 2013/11/1

N2 - During childhood, residents of areas with stable transmission of Plasmodium falciparum parasites acquire substantial protective immunity to malaria, and adults therefore rarely experience clinical disease episodes. However, susceptibility to infection reappears in pregnant women, particularly primigravidae. This is due to appearance of antigenic parasite variants that are restricted to pregnancy. Variant-specific immunity also governs pregnancy-associated recrudescence of Plasmodium berghei infection in pregnant mice. Pregnancy-related changes in the plasma cytokine levels of mice with immunity acquired prior to first pregnancy have not been studied in detail previously, and were the topic of the present study.

AB - During childhood, residents of areas with stable transmission of Plasmodium falciparum parasites acquire substantial protective immunity to malaria, and adults therefore rarely experience clinical disease episodes. However, susceptibility to infection reappears in pregnant women, particularly primigravidae. This is due to appearance of antigenic parasite variants that are restricted to pregnancy. Variant-specific immunity also governs pregnancy-associated recrudescence of Plasmodium berghei infection in pregnant mice. Pregnancy-related changes in the plasma cytokine levels of mice with immunity acquired prior to first pregnancy have not been studied in detail previously, and were the topic of the present study.

U2 - 10.1186/1475-2875-12-387

DO - 10.1186/1475-2875-12-387

M3 - Journal article

C2 - 24180253

VL - 12

SP - 387

JO - Malaria Journal

JF - Malaria Journal

SN - 1475-2875

IS - 1

ER -

ID: 80639167