C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation
Research output: Contribution to journal › Journal article › Research › peer-review
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C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation. / Zacho, Jeppe; Tybjaerg-Hansen, Anne; Jensen, Jan Skov; Grande, Peer; Sillesen, Henrik; Nordestgaard, Børge G.
In: Ugeskrift for læger, Vol. 171, No. 21, 2009, p. 1751-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation
AU - Zacho, Jeppe
AU - Tybjaerg-Hansen, Anne
AU - Jensen, Jan Skov
AU - Grande, Peer
AU - Sillesen, Henrik
AU - Nordestgaard, Børge G
N1 - Keywords: Atherosclerosis; Biological Markers; C-Reactive Protein; Cerebrovascular Disorders; Cohort Studies; Genetic Predisposition to Disease; Genotype; Humans; Myocardial Ischemia; Polymorphism, Genetic; Risk Factors
PY - 2009
Y1 - 2009
N2 - Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease. Udgivelsesdato: 2009-May
AB - Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease. Udgivelsesdato: 2009-May
M3 - Tidsskriftartikel
C2 - 19492468
VL - 171
SP - 1751
EP - 1755
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 21
ER -
ID: 20321552