Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial

Research output: Contribution to journalJournal articleResearchpeer-review

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Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection : a randomised, double-blind, phase 3, non-inferiority trial. / DeJesus, Edwin; Rockstroh, Jürgen K; Henry, Keith; Molina, Jean-Michel; Gathe, Joseph; Ramanathan, Srinivasan; Wei, Xuelian; Yale, Kitty; Szwarcberg, Javier; White, Kirsten; Cheng, Andrew K; Kearney, Brian P; GS-236-0103 Study Team ; Gerstoft, Jan.

In: Lancet, Vol. 379, No. 9835, 2012, p. 2429-38.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

DeJesus, E, Rockstroh, JK, Henry, K, Molina, J-M, Gathe, J, Ramanathan, S, Wei, X, Yale, K, Szwarcberg, J, White, K, Cheng, AK, Kearney, BP, GS-236-0103 Study Team & Gerstoft, J 2012, 'Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial', Lancet, vol. 379, no. 9835, pp. 2429-38. https://doi.org/10.1016/S0140-6736(12)60918-0

APA

DeJesus, E., Rockstroh, J. K., Henry, K., Molina, J-M., Gathe, J., Ramanathan, S., Wei, X., Yale, K., Szwarcberg, J., White, K., Cheng, A. K., Kearney, B. P., GS-236-0103 Study Team, & Gerstoft, J. (2012). Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet, 379(9835), 2429-38. https://doi.org/10.1016/S0140-6736(12)60918-0

Vancouver

DeJesus E, Rockstroh JK, Henry K, Molina J-M, Gathe J, Ramanathan S et al. Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial. Lancet. 2012;379(9835):2429-38. https://doi.org/10.1016/S0140-6736(12)60918-0

Author

DeJesus, Edwin ; Rockstroh, Jürgen K ; Henry, Keith ; Molina, Jean-Michel ; Gathe, Joseph ; Ramanathan, Srinivasan ; Wei, Xuelian ; Yale, Kitty ; Szwarcberg, Javier ; White, Kirsten ; Cheng, Andrew K ; Kearney, Brian P ; GS-236-0103 Study Team ; Gerstoft, Jan. / Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection : a randomised, double-blind, phase 3, non-inferiority trial. In: Lancet. 2012 ; Vol. 379, No. 9835. pp. 2429-38.

Bibtex

@article{e4cc4d3f19cd4b17a6c3f09e5bb485e2,
title = "Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial",
abstract = "The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) into a once-daily, single tablet. We compared EVG/COBI/FTC/TDF with a ritonavir-boosted (RTV) protease inhibitor regimen of atazanavir (ATV)/RTV+FTC/TDF as initial therapy for HIV-1 infection.",
author = "Edwin DeJesus and Rockstroh, {J{\"u}rgen K} and Keith Henry and Jean-Michel Molina and Joseph Gathe and Srinivasan Ramanathan and Xuelian Wei and Kitty Yale and Javier Szwarcberg and Kirsten White and Cheng, {Andrew K} and Kearney, {Brian P} and Jan Gerstoft and Jan Gerstoft",
note = "Copyright {\textcopyright} 2012 Elsevier Ltd. All rights reserved.",
year = "2012",
doi = "10.1016/S0140-6736(12)60918-0",
language = "English",
volume = "379",
pages = "2429--38",
journal = "The Lancet",
issn = "0140-6736",
publisher = "TheLancet Publishing Group",
number = "9835",

}

RIS

TY - JOUR

T1 - Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection

T2 - a randomised, double-blind, phase 3, non-inferiority trial

AU - DeJesus, Edwin

AU - Rockstroh, Jürgen K

AU - Henry, Keith

AU - Molina, Jean-Michel

AU - Gathe, Joseph

AU - Ramanathan, Srinivasan

AU - Wei, Xuelian

AU - Yale, Kitty

AU - Szwarcberg, Javier

AU - White, Kirsten

AU - Cheng, Andrew K

AU - Kearney, Brian P

AU - GS-236-0103 Study Team

AU - Gerstoft, Jan

N1 - Copyright © 2012 Elsevier Ltd. All rights reserved.

PY - 2012

Y1 - 2012

N2 - The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) into a once-daily, single tablet. We compared EVG/COBI/FTC/TDF with a ritonavir-boosted (RTV) protease inhibitor regimen of atazanavir (ATV)/RTV+FTC/TDF as initial therapy for HIV-1 infection.

AB - The HIV integrase strand transfer inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) into a once-daily, single tablet. We compared EVG/COBI/FTC/TDF with a ritonavir-boosted (RTV) protease inhibitor regimen of atazanavir (ATV)/RTV+FTC/TDF as initial therapy for HIV-1 infection.

U2 - 10.1016/S0140-6736(12)60918-0

DO - 10.1016/S0140-6736(12)60918-0

M3 - Journal article

VL - 379

SP - 2429

EP - 2438

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9835

ER -

ID: 48451543