Clonal outbreaks of [Pasteurella] pneumotropica biovar Heyl in two mouse colonies
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Clonal outbreaks of [Pasteurella] pneumotropica biovar Heyl in two mouse colonies. / Adhikary, Sadhana; Bisgaard, Magne; Dagnæs-Hansen, Frederik; Christensen, Henrik.
In: Laboratory Animals, Vol. 51, No. 6, 2017, p. 613-621.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Clonal outbreaks of [Pasteurella] pneumotropica biovar Heyl in two mouse colonies
AU - Adhikary, Sadhana
AU - Bisgaard, Magne
AU - Dagnæs-Hansen, Frederik
AU - Christensen, Henrik
PY - 2017
Y1 - 2017
N2 - The aim of this study was to document the pathogenic role of biovar Heyl of [Pasteurella] pneumotropica in mouse colonies. Fifty-three isolates associated with mastitis and orbital, cutaneous and vaginal abscesses as well as isolates from the nose and vagina of healthy mice were investigated. According to phenotypic characteristics and rpoB sequencing, the isolates were identified as [P.] pneumotropica biovar Heyl. Pulsed-field gel electrophoresis (PFGE) revealed five closely related profiles separated by only one to four fragments. The outbreak strains diverged from epidemiologically unrelated strains with the same rpoB sequence type, as shown by the PFGE profiles. The investigation documented that members of biovar Heyl of [P.] pneumotropica caused disease outbreaks in mouse colonies since the clonality indicated a primary role of [P.] pneumotropica biovar Heyl in the infections observed.
AB - The aim of this study was to document the pathogenic role of biovar Heyl of [Pasteurella] pneumotropica in mouse colonies. Fifty-three isolates associated with mastitis and orbital, cutaneous and vaginal abscesses as well as isolates from the nose and vagina of healthy mice were investigated. According to phenotypic characteristics and rpoB sequencing, the isolates were identified as [P.] pneumotropica biovar Heyl. Pulsed-field gel electrophoresis (PFGE) revealed five closely related profiles separated by only one to four fragments. The outbreak strains diverged from epidemiologically unrelated strains with the same rpoB sequence type, as shown by the PFGE profiles. The investigation documented that members of biovar Heyl of [P.] pneumotropica caused disease outbreaks in mouse colonies since the clonality indicated a primary role of [P.] pneumotropica biovar Heyl in the infections observed.
KW - abscess
KW - mice
KW - PFGE
KW - rpoB
KW - [Pasteurella] pneumotropica
U2 - 10.1177/0023677217698503
DO - 10.1177/0023677217698503
M3 - Journal article
C2 - 28358244
AN - SCOPUS:85034764363
VL - 51
SP - 613
EP - 621
JO - Laboratory Animals
JF - Laboratory Animals
SN - 0023-6772
IS - 6
ER -
ID: 186505961