Chromosome-scale haplotype-resolved pangenomics
Research output: Contribution to journal › Journal article › Research › peer-review
Complete pangenomics is crucial for understanding genetic diversity and evolution across the tree of life. Chromosome-scale, haplotype-resolved pangenomics allows complex structural variations, long-range interactions, and associated functions to be discerned in species populations. We explore the need for high-resolution pangenomes, discuss computational strategies for their development, and describe applications in biodiversity and human health.
Original language | English |
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Journal | Trends in Genetics |
Volume | 38 |
Issue number | 11 |
Pages (from-to) | 1103-1107 |
Number of pages | 5 |
ISSN | 0168-9525 |
DOIs | |
Publication status | Published - 2022 |
Bibliographical note
Publisher Copyright:
© 2022 Elsevier Ltd
- chromosome-scale haplotypes, genome evolution, genome informatics, genomic diversity, pangenomics, reference genome
Research areas
ID: 321540902