Chemical synthesis of dimer ribonucleotides containing internucleotidic phosphorodithioate linkages
Research output: Contribution to journal › Journal article › Research › peer-review
Ribonucleosides, chlorobis(amino)phosphines and thiols react via phosphorothioamidites to form phosphorothioites. Oxidation with sulphur gives ribonucleoside phosphorodithioate triesters which after deprotection yields the phosphorodithioate ribonucleoside analogues.
| Original language | English |
|---|---|
| Journal | Tetrahedron Letters |
| Volume | 31 |
| Issue number | 6 |
| Pages (from-to) | 911-914 |
| Number of pages | 4 |
| ISSN | 0040-4039 |
| DOIs | |
| Publication status | Published - 1 Jan 1990 |
ID: 131117535