Chemical synthesis of dimer ribonucleotides containing internucleotidic phosphorodithioate linkages
Research output: Contribution to journal › Journal article › Research › peer-review
Ribonucleosides, chlorobis(amino)phosphines and thiols react via phosphorothioamidites to form phosphorothioites. Oxidation with sulphur gives ribonucleoside phosphorodithioate triesters which after deprotection yields the phosphorodithioate ribonucleoside analogues.
Original language | English |
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Journal | Tetrahedron Letters |
Volume | 31 |
Issue number | 6 |
Pages (from-to) | 911-914 |
Number of pages | 4 |
ISSN | 0040-4039 |
DOIs | |
Publication status | Published - 1 Jan 1990 |
ID: 131117535