Causes of discrepancies between medications listed in the national electronic prescribing system and patients' actual use of medications
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Causes of discrepancies between medications listed in the national electronic prescribing system and patients' actual use of medications. / Bülow, Cille; Noergaard, Josefine D.S.V.; Færch, Kirstine Ullitz; Pontoppidan, Caroline; Unkerskov, Janne; Johansson, Karl Sebastian; Kornholt, Jonatan; Christensen, Mikkel B.
In: Basic and Clinical Pharmacology and Toxicology, Vol. 129, No. 3, 2021, p. 221-231.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Causes of discrepancies between medications listed in the national electronic prescribing system and patients' actual use of medications
AU - Bülow, Cille
AU - Noergaard, Josefine D.S.V.
AU - Færch, Kirstine Ullitz
AU - Pontoppidan, Caroline
AU - Unkerskov, Janne
AU - Johansson, Karl Sebastian
AU - Kornholt, Jonatan
AU - Christensen, Mikkel B.
N1 - Publisher Copyright: © 2021 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society).
PY - 2021
Y1 - 2021
N2 - Discrepancies between registered prescriptions and patients' actual use of medications are described as frequent and often resulting in adverse medication events. We aimed to assess the extent of and causes behind discrepancies between medications listed in the Danish national prescription system (Shared Medication Record) and patients' actual use of medications. We prospectively reconciled medication for 260 consecutively admitted polypharmacy patients (>50 years and ≥5 prescriptions) at two hospitals in the Capital Region of Denmark. The type of discrepancies were determined and the cause of the discrepancies were evaluated as primarily caused by (1) the patient (i.e., intentional or unintentional non-adherence) or (2) the health care system (i.e., lack of appropriate update of the SMR by physicians in primary or secondary care). There was a median of 12 [IQR 9–15] medications listed and 3 [IQR 1–5] medication discrepancies per patient (total n = 925). The majority (53%) of discrepancies were caused by the health care system, 32% were caused by the patients, of which 70% were intentional non-adherence, and 15% had an indeterminable cause. In conclusion, discrepancies between medications listed in the Shared Medication Record and actual use of medications were frequent and were most often caused by clinicians not updating the prescription information.
AB - Discrepancies between registered prescriptions and patients' actual use of medications are described as frequent and often resulting in adverse medication events. We aimed to assess the extent of and causes behind discrepancies between medications listed in the Danish national prescription system (Shared Medication Record) and patients' actual use of medications. We prospectively reconciled medication for 260 consecutively admitted polypharmacy patients (>50 years and ≥5 prescriptions) at two hospitals in the Capital Region of Denmark. The type of discrepancies were determined and the cause of the discrepancies were evaluated as primarily caused by (1) the patient (i.e., intentional or unintentional non-adherence) or (2) the health care system (i.e., lack of appropriate update of the SMR by physicians in primary or secondary care). There was a median of 12 [IQR 9–15] medications listed and 3 [IQR 1–5] medication discrepancies per patient (total n = 925). The majority (53%) of discrepancies were caused by the health care system, 32% were caused by the patients, of which 70% were intentional non-adherence, and 15% had an indeterminable cause. In conclusion, discrepancies between medications listed in the Shared Medication Record and actual use of medications were frequent and were most often caused by clinicians not updating the prescription information.
KW - drug information
KW - prescription of drugs
KW - rational pharmacotherapy
U2 - 10.1111/bcpt.13626
DO - 10.1111/bcpt.13626
M3 - Journal article
C2 - 34137181
AN - SCOPUS:85112720336
VL - 129
SP - 221
EP - 231
JO - Basic and Clinical Pharmacology and Toxicology
JF - Basic and Clinical Pharmacology and Toxicology
SN - 1742-7835
IS - 3
ER -
ID: 276848783