Case report: Death caused by multi-organ metastatic calcifications as a result of intramuscular injections with paraffin oil
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Case report : Death caused by multi-organ metastatic calcifications as a result of intramuscular injections with paraffin oil. / Jakobsen, Søren Reinhold; Diaz-delCastillo, Marta; Jensen, Martin Blomberg; Andersen, Thomas Levin; Eldrup, Ebbe; Nielsen, Trine Skov.
In: Bone Reports, Vol. 20, 101749, 2024.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Case report
T2 - Death caused by multi-organ metastatic calcifications as a result of intramuscular injections with paraffin oil
AU - Jakobsen, Søren Reinhold
AU - Diaz-delCastillo, Marta
AU - Jensen, Martin Blomberg
AU - Andersen, Thomas Levin
AU - Eldrup, Ebbe
AU - Nielsen, Trine Skov
N1 - Publisher Copyright: © 2024
PY - 2024
Y1 - 2024
N2 - In this forensic case report, we present autopsy findings from a young male in his thirties who had been self-injecting paraffin oil into his upper extremities 8 years prior to death. The injections induced an inflammatory response, leading to granuloma formation. This, in turn, resulted in severe hypercalcemia. The external autopsy examination revealed gross macroscopic ulcerations and enlargement of upper extremities, while calcifications of ligaments, heart, kidneys and dura mater was revealed on postmortem CT-scans. Histopathological examination showed extensive multiorgan metastatic calcifications in several tissues including the lungs, heart and kidney. Cause of death was estimated to be the extensive calcific deposits in the heart likely resulting in cardiac arrest. To our knowledge this is the first case reporting findings from an autopsy in which the cause of death was linked to cosmetic oil injections.
AB - In this forensic case report, we present autopsy findings from a young male in his thirties who had been self-injecting paraffin oil into his upper extremities 8 years prior to death. The injections induced an inflammatory response, leading to granuloma formation. This, in turn, resulted in severe hypercalcemia. The external autopsy examination revealed gross macroscopic ulcerations and enlargement of upper extremities, while calcifications of ligaments, heart, kidneys and dura mater was revealed on postmortem CT-scans. Histopathological examination showed extensive multiorgan metastatic calcifications in several tissues including the lungs, heart and kidney. Cause of death was estimated to be the extensive calcific deposits in the heart likely resulting in cardiac arrest. To our knowledge this is the first case reporting findings from an autopsy in which the cause of death was linked to cosmetic oil injections.
KW - Cosmetic oil injections
KW - Forensic medicine
KW - Hypercalcemia
KW - Paraffinoma
KW - Postmortem computed tomography
U2 - 10.1016/j.bonr.2024.101749
DO - 10.1016/j.bonr.2024.101749
M3 - Journal article
C2 - 38487753
AN - SCOPUS:85187023727
VL - 20
JO - Bone Reports
JF - Bone Reports
SN - 2352-1872
M1 - 101749
ER -
ID: 385689120