Can fecal microbiota transplantation cure irritable bowel syndrome?
Research output: Contribution to journal › Journal article › Research › peer-review
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Can fecal microbiota transplantation cure irritable bowel syndrome? / Halkjær, Sofie Ingdam; Boolsen, Anders Watt; Günther, Stig; Christensen, Alice Højer; Petersen, Andreas Munk.
In: World Journal of Gastroenterology, Vol. 23, No. 22, 14.06.2017, p. 4112-4120.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Can fecal microbiota transplantation cure irritable bowel syndrome?
AU - Halkjær, Sofie Ingdam
AU - Boolsen, Anders Watt
AU - Günther, Stig
AU - Christensen, Alice Højer
AU - Petersen, Andreas Munk
PY - 2017/6/14
Y1 - 2017/6/14
N2 - AIM: To verify the utility of treatment with fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS).METHODS: We searched EMBASE, Cochrane Library and PubMed in March, 2017. The reviewed literature was based on two systematic searches in each of the databases. The MeSH terms used were IBS and fecal microbiota transplantation and the abbreviations IBS and FMT. Reference lists from the articles were reviewed to identify additional pertinent articles.RESULTS: A total of six conference abstracts, one case report, one letter to the editor, and one clinical review were included. In the final analysis, treatment of 48 patients was evaluated. Treatment revealed an improvement in 58% of cases. The varying structure of the nine included studies must be taken into consideration.CONCLUSION: Data on FMT and IBS are too limited to draw sufficient conclusions. Standardized double blinded randomized clinical trials need to be carried out to evaluate the effect of FMT on IBS.
AB - AIM: To verify the utility of treatment with fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome (IBS).METHODS: We searched EMBASE, Cochrane Library and PubMed in March, 2017. The reviewed literature was based on two systematic searches in each of the databases. The MeSH terms used were IBS and fecal microbiota transplantation and the abbreviations IBS and FMT. Reference lists from the articles were reviewed to identify additional pertinent articles.RESULTS: A total of six conference abstracts, one case report, one letter to the editor, and one clinical review were included. In the final analysis, treatment of 48 patients was evaluated. Treatment revealed an improvement in 58% of cases. The varying structure of the nine included studies must be taken into consideration.CONCLUSION: Data on FMT and IBS are too limited to draw sufficient conclusions. Standardized double blinded randomized clinical trials need to be carried out to evaluate the effect of FMT on IBS.
KW - Journal Article
U2 - 10.3748/wjg.v23.i22.4112
DO - 10.3748/wjg.v23.i22.4112
M3 - Journal article
C2 - 28652664
VL - 23
SP - 4112
EP - 4120
JO - World Chinese Journal of Digestology
JF - World Chinese Journal of Digestology
SN - 1009-3079
IS - 22
ER -
ID: 184876319