Brachyspira murdochii colitis in pigs
Research output: Contribution to journal › Journal article › Research › peer-review
The weakly beta-hemolytic porcine spirochete Brachyspira murdochii is considered a normal intestinal commensal. In the present study, however, a field case of B murdochii-associated catarrhal colitis was identified in a pig, as characterized by extensive spirochetal colonization of the surface epithelium. Experimentally, 8 weaned pigs were challenged with the B murdochii isolate, reproducing catarrhal colitis in 2 animals. By applying fluorescent in situ hybridization using a species-specific oligonucleotide probe targeting 23S rRNA, B murdochii organisms were found in high numbers and were closely associated with the surface epithelium in the pigs with catarrhal colitis. The results indicate that, when present in high numbers, B murdochii is low pathogenic for pigs.
Original language | English |
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Journal | Veterinary Pathology |
Volume | 47 |
Issue number | 2 |
Pages (from-to) | 334-338 |
Number of pages | 5 |
ISSN | 0300-9858 |
DOIs | |
Publication status | Published - 2010 |
Externally published | Yes |
- Brachyspira murdochii, Colitis, Infection trial, Swine
Research areas
ID: 339899306