Biomarkører ved diagnostik af Alzheimers sygdom i tidlig fase
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Biomarkører ved diagnostik af Alzheimers sygdom i tidlig fase. / Frederiksen, Kristian S; Hasselbalch, Steen; Law, Ian; Højgaard, Liselotte; Waldemar, Gunhild.
In: Ugeskrift for Laeger, Vol. 177, No. 24, V12140684, 08.06.2015.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Biomarkører ved diagnostik af Alzheimers sygdom i tidlig fase
AU - Frederiksen, Kristian S
AU - Hasselbalch, Steen
AU - Law, Ian
AU - Højgaard, Liselotte
AU - Waldemar, Gunhild
PY - 2015/6/8
Y1 - 2015/6/8
N2 - Alzheimer's disease is responsible for 40-50% of dementia cases. Future treatment may include disease-modifying compounds unlikely to be efficient if administered late in the course, thus necessitating early diagnosis. Furthermore, revised diagnostic research criteria that include biomarkers of pathological accumulation of cortical beta-amyloid (decreased beta-amyloid in cerebrospinal fluid and amyloid imaging) and neurodegeneration (structural MRI and 18F-FDG-PET), have been published. Future research is needed to determine specific evidence-based application of these biomarkers in the clinic as well as discovery of novel biomarkers.
AB - Alzheimer's disease is responsible for 40-50% of dementia cases. Future treatment may include disease-modifying compounds unlikely to be efficient if administered late in the course, thus necessitating early diagnosis. Furthermore, revised diagnostic research criteria that include biomarkers of pathological accumulation of cortical beta-amyloid (decreased beta-amyloid in cerebrospinal fluid and amyloid imaging) and neurodegeneration (structural MRI and 18F-FDG-PET), have been published. Future research is needed to determine specific evidence-based application of these biomarkers in the clinic as well as discovery of novel biomarkers.
M3 - Tidsskriftartikel
C2 - 26058526
VL - 177
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 24
M1 - V12140684
ER -
ID: 161949277