Antimicrobial resistance in the Bacteroides fragilis group in faecal microbiota from healthy Danish children
Research output: Contribution to journal › Journal article › Research › peer-review
The Bacteroides fragilis group constitute a significant portion of the human gut microbiota and comprise a major proportion of anaerobic bacteria isolated in human infections. We established a baseline of antimicrobial susceptibility rates in the B. fragilis group in the intestinal tract of relatively antibiotic-naive healthy Danish children. From 174 faecal samples collected from children attending day care, 359 non-duplicate isolates were screened for antimicrobial susceptibility. Of these, 0.0%, 1.9%, 5.0% and 21.2% of isolates were intermediate-susceptible or resistant to metronidazole, meropenem, piperacillin/tazobactam and clindamycin, respectively. Eighteen additional studies reporting susceptibility rates in the B. fragilis group bacteria were identified by conducting a literature search. Heterogeneity among results from studies of B. fragilis group antimicrobial susceptibility rates in faecal microbiota exists.
Original language | English |
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Journal | International Journal of Antimicrobial Agents |
Volume | 49 |
Issue number | 5 |
Pages (from-to) | 573-578 |
ISSN | 0924-8579 |
DOIs | |
Publication status | Published - 2017 |
- Anti-Bacterial Agents/therapeutic use, Bacteroides Infections/drug therapy, Bacteroides fragilis/drug effects, Child, Clindamycin/therapeutic use, Denmark, Drug Resistance, Bacterial, Feces/microbiology, Humans, Metronidazole/therapeutic use, Microbial Sensitivity Tests, Microbiota/drug effects, Penicillanic Acid/analogs & derivatives, Piperacillin/therapeutic use, Surveys and Questionnaires, Thienamycins/therapeutic use
Research areas
ID: 194917396