An Estimation of the Risk of Pseudotumor Cerebri among Users of the Levonorgestrel Intrauterine Device
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An Estimation of the Risk of Pseudotumor Cerebri among Users of the Levonorgestrel Intrauterine Device. / Valenzuela, Reuben M.; Rai, Ruju; Kirk, Brian H.; Sanders, Jessica N.; Sundar, Subhashree; Hamann, Steffen; Warner, Judith E.A.; Digre, Kathleen B.; Crum, Alison V.; Jones, Kirtly P.; Katz, Bradley J.
In: Neuro-Ophthalmology, Vol. 41, No. 4, 2017, p. 192-197.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - An Estimation of the Risk of Pseudotumor Cerebri among Users of the Levonorgestrel Intrauterine Device
AU - Valenzuela, Reuben M.
AU - Rai, Ruju
AU - Kirk, Brian H.
AU - Sanders, Jessica N.
AU - Sundar, Subhashree
AU - Hamann, Steffen
AU - Warner, Judith E.A.
AU - Digre, Kathleen B.
AU - Crum, Alison V.
AU - Jones, Kirtly P.
AU - Katz, Bradley J.
PY - 2017
Y1 - 2017
N2 - Because of a previous association of pseudotumor cerebri (PTC) with levonorgestrel, we wished to evaluate the use of levonorgestrel-eluting intrauterine devices (“levonorgestrel intrauterine systems”, LNG-IUS) in our University of Utah and Rigshospitalet PTC patients. In our retrospective series, PTC prevalence was approximately 0.18% and 0.15% in the LNG-IUS population versus 0.02% and 0.04% in the non-LNG-IUS population (Utah and Rigshospitalet, respectively), with no significant differences in PTC signs and symptoms among the two groups. Our investigation suggests that women with an LNG-IUS may have increased risk of developing PTC but does not suggest an LNG-IUS can cause PTC.
AB - Because of a previous association of pseudotumor cerebri (PTC) with levonorgestrel, we wished to evaluate the use of levonorgestrel-eluting intrauterine devices (“levonorgestrel intrauterine systems”, LNG-IUS) in our University of Utah and Rigshospitalet PTC patients. In our retrospective series, PTC prevalence was approximately 0.18% and 0.15% in the LNG-IUS population versus 0.02% and 0.04% in the non-LNG-IUS population (Utah and Rigshospitalet, respectively), with no significant differences in PTC signs and symptoms among the two groups. Our investigation suggests that women with an LNG-IUS may have increased risk of developing PTC but does not suggest an LNG-IUS can cause PTC.
KW - Contraception
KW - idiopathic intracranial hypertension
KW - intrauterine system
KW - levonorgestrel
KW - pseudotumor cerebri
U2 - 10.1080/01658107.2017.1304425
DO - 10.1080/01658107.2017.1304425
M3 - Journal article
C2 - 29344058
AN - SCOPUS:85017623884
VL - 41
SP - 192
EP - 197
JO - Neuro-Ophthalmology
JF - Neuro-Ophthalmology
SN - 0165-8107
IS - 4
ER -
ID: 197005086