A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design

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A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial) : study rationale and design. / Kristensen, Peter Lommer; Pedersen-Bjergaard, Ulrik; Beck-Nielsen, Henning; Nørgaard, Kirsten; Perrild, Hans; Christiansen, Jens Sandahl; Jensen, Tonny; Parving, Hans-Henrik; Thorsteinsson, Birger; Tarnow, Lise.

In: B M C Endocrine Disorders, Vol. 12, 2012, p. 10.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kristensen, PL, Pedersen-Bjergaard, U, Beck-Nielsen, H, Nørgaard, K, Perrild, H, Christiansen, JS, Jensen, T, Parving, H-H, Thorsteinsson, B & Tarnow, L 2012, 'A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design', B M C Endocrine Disorders, vol. 12, pp. 10. https://doi.org/10.1186/1472-6823-12-10

APA

Kristensen, P. L., Pedersen-Bjergaard, U., Beck-Nielsen, H., Nørgaard, K., Perrild, H., Christiansen, J. S., Jensen, T., Parving, H-H., Thorsteinsson, B., & Tarnow, L. (2012). A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design. B M C Endocrine Disorders, 12, 10. https://doi.org/10.1186/1472-6823-12-10

Vancouver

Kristensen PL, Pedersen-Bjergaard U, Beck-Nielsen H, Nørgaard K, Perrild H, Christiansen JS et al. A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design. B M C Endocrine Disorders. 2012;12:10. https://doi.org/10.1186/1472-6823-12-10

Author

Kristensen, Peter Lommer ; Pedersen-Bjergaard, Ulrik ; Beck-Nielsen, Henning ; Nørgaard, Kirsten ; Perrild, Hans ; Christiansen, Jens Sandahl ; Jensen, Tonny ; Parving, Hans-Henrik ; Thorsteinsson, Birger ; Tarnow, Lise. / A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial) : study rationale and design. In: B M C Endocrine Disorders. 2012 ; Vol. 12. pp. 10.

Bibtex

@article{08c11a6410844428a6fc681d60c2ff02,
title = "A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial): study rationale and design",
abstract = "Severe hypoglycaemia still represents a significant problem in insulin-treated diabetes. Most patients do not experience severe hypoglycaemia often. However, 20% of patients with type 1 diabetes experience recurrent severe hypoglycaemia corresponding to at least two episodes per year. The effect of insulin analogues on glycaemic control has been documented in large trials, while their effect on the frequency of severe hypoglycaemia is less clear, especially in patients with recurrent severe hypoglycaemia. The HypoAna Trial is designed to investigate whether short-acting and long-acting insulin analogues in comparison with human insulin are superior in reducing the occurrence of severe hypoglycaemic episodes in patients with recurrent hypoglycaemia. This paper reports the study design of the HypoAna Trial.",
author = "Kristensen, {Peter Lommer} and Ulrik Pedersen-Bjergaard and Henning Beck-Nielsen and Kirsten N{\o}rgaard and Hans Perrild and Christiansen, {Jens Sandahl} and Tonny Jensen and Hans-Henrik Parving and Birger Thorsteinsson and Lise Tarnow",
year = "2012",
doi = "10.1186/1472-6823-12-10",
language = "English",
volume = "12",
pages = "10",
journal = "BMC Endocrine Disorders",
issn = "1472-6823",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - A prospective randomised cross-over study of the effect of insulin analogues and human insulin on the frequency of severe hypoglycaemia in patients with type 1 diabetes and recurrent hypoglycaemia (the HypoAna trial)

T2 - study rationale and design

AU - Kristensen, Peter Lommer

AU - Pedersen-Bjergaard, Ulrik

AU - Beck-Nielsen, Henning

AU - Nørgaard, Kirsten

AU - Perrild, Hans

AU - Christiansen, Jens Sandahl

AU - Jensen, Tonny

AU - Parving, Hans-Henrik

AU - Thorsteinsson, Birger

AU - Tarnow, Lise

PY - 2012

Y1 - 2012

N2 - Severe hypoglycaemia still represents a significant problem in insulin-treated diabetes. Most patients do not experience severe hypoglycaemia often. However, 20% of patients with type 1 diabetes experience recurrent severe hypoglycaemia corresponding to at least two episodes per year. The effect of insulin analogues on glycaemic control has been documented in large trials, while their effect on the frequency of severe hypoglycaemia is less clear, especially in patients with recurrent severe hypoglycaemia. The HypoAna Trial is designed to investigate whether short-acting and long-acting insulin analogues in comparison with human insulin are superior in reducing the occurrence of severe hypoglycaemic episodes in patients with recurrent hypoglycaemia. This paper reports the study design of the HypoAna Trial.

AB - Severe hypoglycaemia still represents a significant problem in insulin-treated diabetes. Most patients do not experience severe hypoglycaemia often. However, 20% of patients with type 1 diabetes experience recurrent severe hypoglycaemia corresponding to at least two episodes per year. The effect of insulin analogues on glycaemic control has been documented in large trials, while their effect on the frequency of severe hypoglycaemia is less clear, especially in patients with recurrent severe hypoglycaemia. The HypoAna Trial is designed to investigate whether short-acting and long-acting insulin analogues in comparison with human insulin are superior in reducing the occurrence of severe hypoglycaemic episodes in patients with recurrent hypoglycaemia. This paper reports the study design of the HypoAna Trial.

U2 - 10.1186/1472-6823-12-10

DO - 10.1186/1472-6823-12-10

M3 - Journal article

C2 - 22727048

VL - 12

SP - 10

JO - BMC Endocrine Disorders

JF - BMC Endocrine Disorders

SN - 1472-6823

ER -

ID: 48478717