A model system for perfusion quantification using FAIR
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A model system for perfusion quantification using FAIR. / Andersen, I.K.; Sidaros, Karam; Gesmar, H; Rostrup, Egill; Larsson, H.B.
In: Magnetic Resonance Imaging, Vol. 18, No. 5, 2000, p. 565-574.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A model system for perfusion quantification using FAIR
AU - Andersen, I.K.
AU - Sidaros, Karam
AU - Gesmar, H
AU - Rostrup, Egill
AU - Larsson, H.B.
PY - 2000
Y1 - 2000
N2 - Flow-sensitive experiments (FAIR) have been performed on a tube-flow phantom in order to validate quantitative perfusion measurements on humans. A straight-forward correspondence between perfusion and bulk-flow is found. It is shown that the flow phantom model only holds when the slice profiles of the involved RF pulses are taken into account. A small flow-independent off-set may be present in the data. The off-set is explained by the model. Based on the correspondence between the phantom and the in vivo models, it is shown that the lowest flow values that could be measured in the phantom correspond to perfusion values lower than the cortical perfusion in the brain. Thus, the experimental accuracy and the computational methods for quantitative perfusion measurements in vivo can be validated by a tube-flow phantom
AB - Flow-sensitive experiments (FAIR) have been performed on a tube-flow phantom in order to validate quantitative perfusion measurements on humans. A straight-forward correspondence between perfusion and bulk-flow is found. It is shown that the flow phantom model only holds when the slice profiles of the involved RF pulses are taken into account. A small flow-independent off-set may be present in the data. The off-set is explained by the model. Based on the correspondence between the phantom and the in vivo models, it is shown that the lowest flow values that could be measured in the phantom correspond to perfusion values lower than the cortical perfusion in the brain. Thus, the experimental accuracy and the computational methods for quantitative perfusion measurements in vivo can be validated by a tube-flow phantom
U2 - http://dx.doi.org/10.1016/S0730-725X(00)00136-3
DO - http://dx.doi.org/10.1016/S0730-725X(00)00136-3
M3 - Journal article
VL - 18
SP - 565
EP - 574
JO - Magnetic Resonance Imaging
JF - Magnetic Resonance Imaging
SN - 0730-725X
IS - 5
ER -
ID: 34159519